Peptide Database

Peptide NameAntileukoproteinase (ALP) (Secretory leukocyte protease inhibitor)

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Anti-Mycobacterium

Antiparasitic ▸ General antiparasitic ▸ Antiparasitic

Enzyme modulation ▸ Enzyme inhibition ▸ Protease inhibition

Other / Curated residual function label ▸ Generic enzyme inhibition annotation

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Wound healing/Regeneration ▸ Wound healing

Standard StatusStandard

Sequence Length132 amino acids

Chemical FormulaC616H1000N170O175S19

DescriptionStandard

        MKFSGLFPFLLLALGTLALWAVEGAENEALKAGACPPRKSAQCFGNEKPRCSSDWQCPHKKKCCLDTCGTECLDPVNITNPVKKKPGTCPVIHGQCLMLKPLNHCETDDQCIGALKCCKAMCGKVCLSPVKA
    

Molecular Weight14196.80 Da

Isoelectric Point (pI)8.59

Net Charge (pH 7.0)5.61

Net Charge (pH 7.4) 4.97

Charge Density (pH 7.0) 0.0425

GRAVY Index-0.05

Hydrophobic Moment 0.48

Boman Index0.05

Instability Index33.39

Aliphatic Index 74.70

Aromaticity 0.0455

Extinction Coeff. Reduced 11000.00

Extinction Coeff. Oxidized 12000.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 5431.09

LogP -54.06

H-bond Donors 195.0

H-bond Acceptors 203.0

Rotatable Bonds 466.0

Heavy Atoms 980.0

Ring Count 22.0

Amide Bonds 140.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0385745 VERIFIED: YES

Provenance & Taxonomy

OrganismOvis aries [Animal]

Tax ID9940

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Antiparasitic Anti-tuberculosis Protease inhibitor Serine protease inhibitor Wound healing Enzyme inhibitory Non-hemolytic