Peptide Database

Peptide NameBeta-defensin

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibiotic activity

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length88 amino acids

Chemical FormulaC401H656N116O120S12

DescriptionStandard

        LSISYFKIMAFLLLFRCLCNWYVRKCANKTGNCRSTCRNGERVINPPTGMCSKEKLCCILDNGCSKTVPPGGSSMTSAATGGSTTGIA
    

Molecular Weight9406.98 Da

Isoelectric Point (pI)9.26

Net Charge (pH 7.0)7.67

Net Charge (pH 7.4) 7.32

Charge Density (pH 7.0) 0.0872

GRAVY Index0.04

Hydrophobic Moment 0.80

Boman Index0.05

Instability Index20.45

Aliphatic Index 68.75

Aromaticity 0.0682

Extinction Coeff. Reduced 8480.00

Extinction Coeff. Oxidized 8980.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 3796.08

LogP -47.60

H-bond Donors 144.0

H-bond Acceptors 140.0

Rotatable Bonds 309.0

Heavy Atoms 649.0

Ring Count 11.0

Amide Bonds 93.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0040574 VERIFIED: NO

Provenance & Taxonomy

OrganismBos indicus x Bos taurus [Animal]

FamilyDefensin

Tax ID30522

Structure & Mods

Configlinear polypeptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Defensin Non-hemolytic

MethodQualitative functional evidence

RECORD: Rec_0090065 VERIFIED: NO

Provenance & Taxonomy

OrganismBos mutus grunniens (Wild yak) [Animal]

FamilyDefensin

Structure & Mods

Configdisulfide-stabilized linear peptide scaffold [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Defensin