Peptide Database

Peptide NamePeptide 8

Function Ontology

Antimicrobial

Antiparasitic ▸ Antimalarial

Antiparasitic ▸ General antiparasitic ▸ Antiparasitic

Enzyme modulation ▸ Enzyme inhibition ▸ Protease inhibition

Standard StatusStandard

Sequence Length7 amino acids

Chemical FormulaC34H54N8O9

DescriptionStandard

        VLLNGGF
    

Molecular Weight718.84 Da

Isoelectric Point (pI)5.50

Net Charge (pH 7.0)-0.27

Net Charge (pH 7.4) -0.48

Charge Density (pH 7.0) -0.0380

GRAVY Index1.47

Hydrophobic Moment 0.21

Boman Index0.65

Instability Index4.73

Aliphatic Index 152.86

Aromaticity 0.1429

Extinction Coeff. Reduced 0.00

Extinction Coeff. Oxidized 0.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 281.01

LogP -1.56

H-bond Donors 9.0

H-bond Acceptors 9.0

Rotatable Bonds 22.0

Heavy Atoms 51.0

Ring Count 1.0

Amide Bonds 7.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0134892 VERIFIED: YES

Provenance & Taxonomy

Organismsynthetic construct [Synthetic]

FamilySynthetic peptide

Tax ID32630

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

N-TermNone

C-TermNone

Other ModsFumaric acid (Fum)

Bio-Activity Profile

Function

Antimicrobial Cysteine protease inhibitor Antiparasitic Antimalarial

TargetPlasmodium falciparum FCBR

Activity74±9 μM

MethodIC50; Fluorimetry (SYTOX Green dye)