Peptide Database

Peptide NameColicin-D

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative

Antimicrobial ▸ Antibiotic activity

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length461 amino acids

Chemical FormulaC2140H3409N587O657S20

DescriptionStandard

        MTDTTDEGTVTMKPPAYYRDGVPYDANGQAVTLPPGDTPPPLVTDLGDGSFQFKSQKKACYLMNINALGSTWTMNRDDGGVAACFATEEEKQVAVRLMTGLMPAPEYTAEQADAAMLMLGAPGALALSGGQWSMQLSVAGEGVMTFGDTLAGALTAAIRRGMALLTASTAGPMAMAASTLLFSSPAGEGSGRVPGRNLEAMFALNAKLLAGKNVTGGPGATHIDLPVRGALVNRNGELALALLKTGSGIPAAVQVLHAVRDTATGLDIITLPTMAGEPPRSILINPAPVPAGPSDTGHHRPVPVTPVHTGTNVTPVETLVVTPPSGDISPGGLRDFIYWRPNAAGTGVEPVYVMLSDPLDSGRFTRKQLDKKYKHAGDFGVSDPKKNSETLTKFRDAIEAHMSDKETVEKGIYRRVKGSKVYFNPESMNVVILKNDGKWLSGWKINPDADNGKIYLETGEL
    

Molecular Weight48513.80 Da

Isoelectric Point (pI)5.87

Net Charge (pH 7.0)-4.86

Net Charge (pH 7.4) -5.56

Charge Density (pH 7.0) -0.0105

GRAVY Index-0.16

Hydrophobic Moment 0.57

Boman Index0.09

Instability Index31.83

Aliphatic Index 79.83

Aromaticity 0.0586

Extinction Coeff. Reduced 43890.00

Extinction Coeff. Oxidized 44015.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0273664 VERIFIED: YES

Provenance & Taxonomy

OrganismEnterobacteriaceae bacterium RIT693 [Bacterium]

FamilyPyocin/Colicin

Tax ID2666197

Structure & Mods

Configgene-encoded linear polypeptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Bacteriocin Anti-Gram-negative Non-hemolytic Non-ribosomal

TargetEscherichia coli