Peptide Database

Peptide NameGambicin

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative

Standard StatusStandard

Sequence Length33 amino acids

Chemical FormulaC147H238N46O45S4

DescriptionStandard

        APTCARCKSIGARYCGYGYLNRKGVSCDGQVSI
    

Molecular Weight3498.00 Da

Isoelectric Point (pI)9.17

Net Charge (pH 7.0)3.75

Net Charge (pH 7.4) 3.50

Charge Density (pH 7.0) 0.1137

GRAVY Index-0.18

Hydrophobic Moment 0.38

Boman Index-0.04

Instability Index13.82

Aliphatic Index 62.12

Aromaticity 0.0909

Extinction Coeff. Reduced 4470.00

Extinction Coeff. Oxidized 4720.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 1488.56

LogP -19.33

H-bond Donors 58.0

H-bond Acceptors 53.0

Rotatable Bonds 113.0

Heavy Atoms 242.0

Ring Count 4.0

Amide Bonds 34.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0326487 VERIFIED: YES

Provenance & Taxonomy

OrganismAnopheles gambiae [Animal]

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Anti-Gram-negative

TargetEscherichia coli TOP10

MethodMex pooled growth assay (OD_ID at 4.5 h; Wald adjusted p-value)