Peptide Database

Peptide NameBeta-defensin

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibiotic activity

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length68 amino acids

Chemical FormulaC356H580N98O86S9

DescriptionStandard

        MKLLVLTLAMLLLTAHLTPGDAQKCWNLLGKCRHRCTKKEGVYVYCTNGKMCCVKPKYQPKQKPRWLF
    

Molecular Weight7897.60 Da

Isoelectric Point (pI)9.77

Net Charge (pH 7.0)10.61

Net Charge (pH 7.4) 10.18

Charge Density (pH 7.0) 0.1560

GRAVY Index-0.19

Hydrophobic Moment 0.53

Boman Index-0.03

Instability Index32.42

Aliphatic Index 84.56

Aromaticity 0.0882

Extinction Coeff. Reduced 15470.00

Extinction Coeff. Oxidized 15845.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 2964.59

LogP -20.20

H-bond Donors 109.0

H-bond Acceptors 108.0

Rotatable Bonds 263.0

Heavy Atoms 549.0

Ring Count 14.0

Amide Bonds 72.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0067559 VERIFIED: NO

Provenance & Taxonomy

OrganismCavia porcellus [Animal]

FamilyDefensin

Structure & Mods

ConfigSingle-chain peptide backbone represented as a linear sequence entry [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial

RECORD: Rec_0355715 VERIFIED: NO

Provenance & Taxonomy

OrganismCavia porcellus [Animal]

FamilyDefensin

Tax ID10141

Structure & Mods

Configlinear polypeptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Defensin Non-hemolytic

MethodQualitative functional evidence