Peptide Database

Peptide NameSLAY-screened peptide P1736

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial

Standard StatusStandard

Sequence Length20 amino acids

Chemical FormulaC99H152N38O31

DescriptionStandard

        RNKGHQTRYTANGGQYREHP
    

Molecular Weight2370.50 Da

Isoelectric Point (pI)10.27

Net Charge (pH 7.0)2.93

Net Charge (pH 7.4) 2.62

Charge Density (pH 7.0) 0.1467

GRAVY Index-2.31

Hydrophobic Moment 0.35

Boman Index-0.56

Instability Index-3.53

Aliphatic Index 5.00

Aromaticity 0.1000

Extinction Coeff. Reduced 2980.00

Extinction Coeff. Oxidized 2980.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 1167.09

LogP -16.32

H-bond Donors 41.0

H-bond Acceptors 36.0

Rotatable Bonds 77.0

Heavy Atoms 168.0

Ring Count 5.0

Amide Bonds 23.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0256803 VERIFIED: YES

Provenance & Taxonomy

Organismsynthetic construct [Synthetic]

Tax ID32630

Structure & Mods

Configlinear peptide [Linear]

Chiralitystereochemistry not specified [Other]

Bio-Activity Profile

Function

Antimicrobial Antibacterial

Targetrecombinant Escherichia coli surface-display screening

MethodSLAY screening

PaperAshley T Tucker, Sean P Leonard, Cory D DuBois, Gregory A Knauf, Ashley L Cunningham, Claus O Wilke, M Stephen Trent, Bryan W Davies. Discovery of Next-Generation Antimicrobials through Bacterial Self-Screening of Surface-Displayed Peptide Libraries. Cell. 2018 Jan 25;172(3):618-628.e13. doi: 10.1016/j.cell.2017.12.009. Epub 2018 Jan 4. PMID29307492 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/29307492/