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MYP_016603
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Basic Information
AS-hepc2
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive
Antimicrobial ▸ Antifungal
Standard
24 amino acids
C98H156N34O27S9
Standard
Sequence
SPAGCRFCCGCCPNMRGCGVCCRF
Physicochemical Analysis
2531.08 Da
8.53
2.38
2.06
0.0992
0.45
0.44
0.03
37.26
16.25
0.0833
0.00
500.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
964.06
-13.90
42.0
39.0
76.0
168.0
4.0
24.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0089359 VERIFIED: YES
Provenance & Taxonomy
Acanthopagrus schlegelii [Animal]
Hepcidin
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial
PMID21073978 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/21073978/
RECORD: Rec_0120915 VERIFIED: YES
Provenance & Taxonomy
Acanthopagrus schlegelii [Animal]
Hepcidin
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-negative
Escherichia coli
5 μM
MIC
RECORD: Rec_0176021 VERIFIED: YES
Provenance & Taxonomy
Acanthopagrus schlegelii [Animal]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
-
Escherichia coli TOP10
Mex pooled growth assay (OD_ID at 4.5 h; Wald adjusted p-value)
PaperKoch P, Schmitt S, Cardner M, Beerenwinkel N, Panke S, Held M. Discovery of antimicrobials by massively parallelized growth assays (Mex). Scientific Reports. 2022;12:4097. doi:10.1038/s41598-022-07755-7 PMID35260685 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/35260685/
RECORD: Rec_0229483 VERIFIED: YES
Provenance & Taxonomy
Acanthopagrus schlegelii [Animal]
Hepcidin
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive
Staphylococcus aureus
1.25 μM
MIC
RECORD: Rec_0233161 VERIFIED: NO
Provenance & Taxonomy
not reported [other]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
None
Bio-Activity Profile
Antibacterial Antimicrobial Antifungal Anti-Gram-positive Anti-Gram-negative
PaperCAMP: Collection of sequences and structures of antimicrobial peptides PMID24265220 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/24265220/
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