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MYP_016583
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Basic Information
D1-NH2
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive
Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic
Standard
10 amino acids
C59H99N19O14
Standard
Sequence
SGKLYYRRKK
Physicochemical Analysis
1298.54 Da
10.56
4.46
4.24
0.4455
-2.07
0.27
-0.77
44.73
39.00
0.2000
2980.00
2980.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
587.77
-4.76
23.0
19.0
46.0
92.0
2.0
9.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0080203 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
topology not specified [Not included yet]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative
Pseudomonas aeruginosa ATCC 27853
100 μM
MIC
PaperPubMed PMID: 22518150 | PubMed PMID: 23860860 PMID22518150;23860860 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/22518150/
RECORD: Rec_0129251 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
topology not specified [Not included yet]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative Hemolytic
human red blood cells
PaperPubMed PMID: 22518150 | PubMed PMID: 23860860 PMID22518150;23860860 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/22518150/
RECORD: Rec_0177904 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
topology not specified [Not included yet]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative Hemolytic
PaperPubMed PMID: 22518150 | PubMed PMID: 23860860 PMID22518150;23860860 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/22518150/
RECORD: Rec_0259885 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Brevinin
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial
Escherichia coli
12
MIC
PMID23860860 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/23860860/
RECORD: Rec_0269894 VERIFIED: YES
Provenance & Taxonomy
Synthetic construct [Synthetic]
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial
Pseudomonas aeruginosa
>100 μM
MIC
PaperDesign of short membrane selective antimicrobial peptides containing tryptophan and arginine residues for improved activity, salt-resistance, and biocompatibility.
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