Peptide Database

Peptide NameBactericidal permeability-increasing protein

Function Ontology

Anticancer ▸ Cytotoxic anticancer activity ▸ Cytotoxic

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative

Antimicrobial ▸ Antibiotic activity

Toxicity / Safety ▸ Cytotoxicity ▸ Cytotoxic

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Venom / Toxin ▸ General toxin ▸ Cytotoxic

Standard StatusStandard

Sequence Length228 amino acids

Chemical FormulaC1147H1819N283O335S9

DescriptionStandard

        LKNLNEMLCPIIASEVKALNANLSTLEVLTKIDNYTLLDYSLISSPEITENYLVLNLKGVFYPLENLADPPFSPVPFVLPERSNSMLYIGIAEYFFKSASFAYFTAGAFNVTLSTKEISNHFVQNSQGLGNVLSRIAEIYILSQPFMVRIMATEPPVINLQPGNFTLDIPASIMMLTQPKNSTVETIVSMDFVASTSVGLVILGQRLVCSLSLNRFRLALPESNRSNI
    

Molecular Weight25221.99 Da

Isoelectric Point (pI)5.05

Net Charge (pH 7.0)-4.15

Net Charge (pH 7.4) -4.48

Charge Density (pH 7.0) -0.0182

GRAVY Index0.31

Hydrophobic Moment 0.63

Boman Index0.20

Instability Index42.66

Aliphatic Index 111.58

Aromaticity 0.0921

Extinction Coeff. Reduced 11920.00

Extinction Coeff. Oxidized 12045.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0337869 VERIFIED: NO

Provenance & Taxonomy

OrganismMacaca mulatta [Animal]

Tax ID9544

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Anti-Gram-negative Cytotoxic Non-hemolytic Non-ribosomal

TargetGram-negative bacteria

MethodQualitative functional evidence