Peptide Database

Peptide NameBactericidal permeability-increasing protein (BPI)

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative

Antimicrobial ▸ Antibiotic activity

Venom / Toxin ▸ General toxin ▸ Cytotoxin

Standard StatusStandard

Sequence Length176 amino acids

Chemical FormulaC884H1391N237O240S7

DescriptionStandard

        PMTPPVEHEPMLLLAVTEFVANSAAFTYFTAGALHRNISTLPRRFPLQLSTKSMEVFSPQLQEHYPDQPMELHLWARQQPLLSCHPDALHGTLFSSAEAFVVLPNATRVPAFLLNIDANVTGKPTITRNRLGGTVRLTGLGLPVLQVKRLETVLKFGLWLFGVPQANSKCCPSPVP
    

Molecular Weight19403.40 Da

Isoelectric Point (pI)9.01

Net Charge (pH 7.0)3.47

Net Charge (pH 7.4) 3.04

Charge Density (pH 7.0) 0.0197

GRAVY Index0.07

Hydrophobic Moment 0.82

Boman Index0.13

Instability Index58.69

Aliphatic Index 95.28

Aromaticity 0.0795

Extinction Coeff. Reduced 13980.00

Extinction Coeff. Oxidized 14105.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 7457.10

LogP -78.80

H-bond Donors 254.0

H-bond Acceptors 256.0

Rotatable Bonds 608.0

Heavy Atoms 1368.0

Ring Count 41.0

Amide Bonds 190.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0151186 VERIFIED: NO

Provenance & Taxonomy

OrganismCopsychus sechellarum [Animal]

FamilyBPI

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Anti-Gram-negative Cytotoxin

TargetGram-negative bacteria