MYP_016532
Oncocin [P13Hyp,R15Hyp,I16Tle,R19Orn], Onc110
Anticancer
Anticancer
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Cytotoxic anticancer activity
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Cytotoxic
Antimicrobial
Antimicrobial
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Antibacterial
Toxicity / Safety
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Blood cell toxicity
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Hemolysis
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Hemolytic
Toxicity / Safety
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Cytotoxicity
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Cytotoxic
Venom / Toxin
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General toxin
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Cytotoxic
not Standard
19 amino acids
-
contains X representing unresolved or non-standard residue
VDKPPYLPRPRPXRXXYNX
0.00 Da
0.00
0.00
0.00
0.00
0.00
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Amino Acid Composition
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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RECORD: Rec_0245639
VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
synthetic linear peptide [Linear]
noncanonical stereochemical modification [Modified]
unspecified non-canonical residue at 13,15,16,19
Bio-Activity Profile
Antimicrobial
Antibacterial
Escherichia coli 70419002
1 μg/mL
MIC
RECORD: Rec_0251030
VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
synthetic linear peptide [Linear]
noncanonical stereochemical modification [Modified]
unspecified non-canonical residue at 13,15,16,19
Bio-Activity Profile
Antimicrobial
Antibacterial
Salmonella enterica subsp. enterica serovar Typhimurium ATCC 14028
4.5 μg/mL
MIC
RECORD: Rec_0253786
VERIFIED: YES
Provenance & Taxonomy
Synthetic construct [Synthetic]
Oncocin
32630
Structure & Mods
synthetic linear peptide [Linear]
mixed L/D or modified amino-acid peptide [Mixed]
None
Amidation
x=trans-4-hydroxyproline; X(16)=tert-Leu; X(19)=Orn
Bio-Activity Profile
Antimicrobial
Anticancer
Cytotoxic
μg/ml
600 μg/mL
Cytotoxicity
RECORD: Rec_0259209
VERIFIED: YES
Provenance & Taxonomy
Synthetic construct [Synthetic]
Oncocin
32630
Structure & Mods
synthetic linear peptide [Linear]
mixed L/D or modified amino-acid peptide [Mixed]
None
Amidation
x=trans-4-hydroxyproline; X(16)=tert-Leu; X(19)=Orn
Bio-Activity Profile
Antimicrobial
Anticancer
HepG2 (Not active up to 600 μg/ml)
RECORD: Rec_0279604
VERIFIED: YES
Provenance & Taxonomy
Synthetic construct [Synthetic]
Oncocin
32630
Structure & Mods
synthetic linear peptide [Linear]
mixed L/D or modified amino-acid peptide [Mixed]
None
Amidation
x=trans-4-hydroxyproline; X(16)=tert-Leu; X(19)=Orn
Bio-Activity Profile
Antimicrobial
Anticancer
Tumor cells: SH-SY5Y (<5% Cytotoxicity=600 μg/ml)
Showing 5 records on this page · Page 9 of 14