MYP_016532
Basic Information
Oncocin [P13Hyp,R15Hyp,I16Tle,R19Orn], Onc110
Anticancer
Anticancer Cytotoxic anticancer activity Cytotoxic
Antimicrobial
Antimicrobial Antibacterial
Toxicity / Safety Blood cell toxicity Hemolysis Hemolytic
Toxicity / Safety Cytotoxicity Cytotoxic
Venom / Toxin General toxin Cytotoxic
not Standard
19 amino acids
-
contains X representing unresolved or non-standard residue
Sequence
VDKPPYLPRPRPXRXXYNX
Physicochemical Analysis
0.00 Da
0.00
0.00
0.00
0.00
0.00
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Residue Composition
Amino Acid Composition
Chemical Descriptors
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0115801 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
synthetic linear peptide [Linear]
noncanonical stereochemical modification [Modified]
unspecified non-canonical residue at 13,15,16,19
Bio-Activity Profile
Antimicrobial Antibacterial
Proteus vulgaris ICB 9081
4 μg/mL
MIC
RECORD: Rec_0123844 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
synthetic linear peptide [Linear]
noncanonical stereochemical modification [Modified]
unspecified non-canonical residue at 13,15,16,19
Bio-Activity Profile
Antimicrobial Antibacterial
Pseudomonas aeruginosa PAO1
0.5 μg/mL
MIC
RECORD: Rec_0129105 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
synthetic linear peptide [Linear]
noncanonical stereochemical modification [Modified]
unspecified non-canonical residue at 13,15,16,19
Bio-Activity Profile
Antimicrobial Antibacterial
Klebsiella pneumoniae DSM 11678
128 μg/mL
MIC
RECORD: Rec_0133173 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Oncocin
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
Amidation
X(13)= 4-Hydroxyproline; X(15)= 4-Hydroxyproline; X(16)=L-tert-leucine; X(19)=Orn
Bio-Activity Profile
Antimicrobial Anticancer
HeLa (Not active up to 2000μg/ml)
RECORD: Rec_0137472 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
synthetic linear peptide [Linear]
noncanonical stereochemical modification [Modified]
unspecified non-canonical residue at 13,15,16,19
Bio-Activity Profile
Antimicrobial Antibacterial
Klebsiella pneumoniae 63
2 μg/mL
MIC
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