‹ ›
MYP_016525
← PREVIOUS NEXT → BACK
Basic Information
Ac-Tric
Anticancer
Anticancer ▸ Cytotoxic anticancer activity ▸ Cytotoxic
Antimicrobial
Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic
Toxicity / Safety ▸ Cytotoxicity ▸ Cytotoxic
Venom / Toxin ▸ General toxin ▸ Cytotoxic
not Standard
11 amino acids
-
contains X representing unresolved or non-standard residue
Sequence
XGLXGGLXGIX
Physicochemical Analysis
0.00 Da
0.00
0.00
0.00
0.00
0.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
Structural Visualization
3D PDB MODEL
Drag to rotate. Click a residue or atom to inspect it; the selected residue is highlighted in amber in the current view mode. Use the buttons to zoom.
2D CHEMICAL STRUCTURE
Drag to move
Drag to move. Use the buttons to zoom.
Experimental Records
RECORD: Rec_0195736 VERIFIED: YES
Provenance & Taxonomy
Synthetic construct [Synthetic]
32630
Structure & Mods
synthetic linear peptide [Linear]
canonical L-amino-acid peptide [L]
Oct (Fatty acid 1-Octanoyl)
None
X(1)=TOAC; X(4)=Api; X(8)=Aib; X(11)=Lol (Amino alcohol leucinol)
Bio-Activity Profile
Antimicrobial Anticancer
HeLa (Not active up to 20 μM)
PaperThe rational search for selective anticancer derivatives of the peptide Trichogin GA IV: a multi-technique biophysical approach. Sci Rep. 2016 Apr 4;6:24000. doi: 10.1038/srep24000. PMID: 27039838. PMID27039838 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/27039838/
RECORD: Rec_0204421 VERIFIED: YES
Provenance & Taxonomy
Trichoderma longibrachiatum [Fungus]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Oct (Fatty acid 1-Octanoyl)
None
X(1/4/8)=Aib; X(11)=Lol (Amino alcohol leucinol)
Bio-Activity Profile
Antimicrobial Anticancer
Tumor cells: T67
8 μM
EC50
PaperThe rational search for selective anticancer derivatives of the peptide Trichogin GA IV: a multi-technique biophysical approach. Sci Rep. 2016 Apr 4;6:24000. doi: 10.1038/srep24000. PMID: 27039838. PMID27039838 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/27039838/
RECORD: Rec_0216742 VERIFIED: YES
Provenance & Taxonomy
Trichoderma longibrachiatum [Fungus]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Oct (Fatty acid 1-Octanoyl)
None
X(1/4/8)=Aib; X(11)=Lol (Amino alcohol leucinol)
Bio-Activity Profile
Antimicrobial Anticancer
Tumor cells: T67
1 μM
EC50
PaperThe rational search for selective anticancer derivatives of the peptide Trichogin GA IV: a multi-technique biophysical approach. Sci Rep. 2016 Apr 4;6:24000. doi: 10.1038/srep24000. PMID: 27039838. PMID27039838 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/27039838/
RECORD: Rec_0217804 VERIFIED: YES
Provenance & Taxonomy
Synthetic construct [Synthetic]
32630
Structure & Mods
synthetic linear peptide [Linear]
canonical L-amino-acid peptide [L]
Oct (Fatty acid 1-Octanoyl)
None
X(1)=TOAC; X(4)=Api; X(8)=Aib; X(11)=Lol (Amino alcohol leucinol)
Bio-Activity Profile
Antimicrobial Anticancer Cytotoxic
μM
20 μM
Cytotoxicity
PaperThe rational search for selective anticancer derivatives of the peptide Trichogin GA IV: a multi-technique biophysical approach. Sci Rep. 2016 Apr 4;6:24000. doi: 10.1038/srep24000. PMID: 27039838. PMID27039838 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/27039838/
RECORD: Rec_0225144 VERIFIED: YES
Provenance & Taxonomy
Trichoderma longibrachiatum [Fungus]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Oct (Fatty acid 1-Octanoyl)
None
X(1/4/8)=Aib; X(11)=Lol (Amino alcohol leucinol)
Bio-Activity Profile
Antimicrobial Anticancer
Tumor cells: T67
13 μM
EC50
PaperThe rational search for selective anticancer derivatives of the peptide Trichogin GA IV: a multi-technique biophysical approach. Sci Rep. 2016 Apr 4;6:24000. doi: 10.1038/srep24000. PMID: 27039838. PMID27039838 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/27039838/
FIRST PREV 1 ... 3 4 5 6 7 ... 10 NEXT LAST
Showing 5 records on this page · Page 5 of 10