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MYP_016450
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Basic Information
Neuropeptide A-18-F/NPAF
Cardiovascular
Hormonal / Endocrine ▸ Hormone peptide
Neurological / Signaling ▸ Analgesic/opioid activity ▸ Analgesic
Neurological / Signaling ▸ Neuromodulation
Neurological / Signaling ▸ Neuropeptide activity ▸ Neuropeptide
Neurological / Signaling ▸ Pain modulation ▸ Pronociceptive activity
Regulatory peptide ▸ Biological modulation
Regulatory peptide ▸ Cell-cell communication
Standard
18 amino acids
C90H131N25O26
Standard
Sequence
AGEGLNSQFWSLAAPQRF
Physicochemical Analysis
1979.15 Da
6.05
-0.20
-0.39
-0.0112
-0.27
0.30
0.12
33.17
60.00
0.1667
5500.00
5500.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
833.95
-8.71
28.0
26.0
61.0
141.0
5.0
20.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0029523 VERIFIED: NO
Provenance & Taxonomy
Homo sapiens [Animal]
9606
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Amidation
Bio-Activity Profile
Neuropeptide
RECORD: Rec_0137229 VERIFIED: NO
Provenance & Taxonomy
Homo sapiens [Animal]
Neuropeptide AF
9606
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Amidation
Bio-Activity Profile
Analgesic Pronociceptive Hormone Endocrine Neuropeptide Neuromodulator Cardiovascular Receptor modulation
Mammalian: 4.4 hour; Yeast: >20 hour; E. coli: >10 hour
RECORD: Rec_0225121 VERIFIED: YES
Provenance & Taxonomy
not reported [other]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Neuropeptide
Paper数据库级溯源文献：Wang Y, Wang M, Yin S, et al. NeuroPep: a comprehensive resource of neuropeptides. Database (Oxford). 2015:bav038. PMID 25931458; Bin Y, Zhang W, Tang W, et al. Prediction of Neuropeptides from Sequence Information Using Ensemble Classifier and Hybrid Features. J Proteome Res. 2020;19(9):3732-3740. PMID 32786686. PMID25931458;32786686 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/25931458/
RECORD: Rec_0370009 VERIFIED: NO
Provenance & Taxonomy
Homo sapiens [Animal]
FMRFamide related peptide
9606
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Amidation
Bio-Activity Profile
RFamide Neuropeptide Neuromodulator
Evidence URLhttps://www.uniprot.org/uniprotkb/NPFF_HUMAN/entry
RECORD: Rec_0422094 VERIFIED: YES
Provenance & Taxonomy
not reported [other]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
None
Bio-Activity Profile
Cell-Cell Communication
PaperNeuroPedia: neuropeptide database and spectral library PMID21821666 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/21821666/