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MYP_016404
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Basic Information
Magainin 2 [F12W]-C
Antimicrobial
Antimicrobial ▸ Antibacterial
Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic
not Standard
25 amino acids
-
contains X representing unresolved or non-standard residue
Sequence
GIGKFLHSAKKWGKAFVGEIMNSXC
Physicochemical Analysis
0.00 Da
0.00
0.00
0.00
0.00
0.00
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Residue Composition
Amino Acid Composition
Chemical Descriptors
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0074604 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Magainin
32630
Structure & Mods
synthetic linear peptide [Linear]
noncanonical stereochemical modification [Modified]
unspecified non-canonical residue at 24
Bio-Activity Profile
Antimicrobial Antibacterial
Bacillus subtilis IFO 3134
27 μg/mL
MIC
PMID12450326 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/12450326/
RECORD: Rec_0075027 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Magainin
32630
Structure & Mods
synthetic linear peptide [Linear]
noncanonical stereochemical modification [Modified]
unspecified non-canonical residue at 24
Bio-Activity Profile
Antimicrobial Antibacterial
Pseudomonas aeruginosa IFO 12582
13 μg/mL
MIC
PMID12450326 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/12450326/
RECORD: Rec_0186647 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Magainin
32630
Structure & Mods
synthetic linear peptide [Linear]
noncanonical stereochemical modification [Modified]
unspecified non-canonical residue at 24
Bio-Activity Profile
Antimicrobial Antibacterial
Staphylococcus aureus IFO 12732
27 μg/mL
MIC
PMID12450326 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/12450326/
RECORD: Rec_0331908 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Magainin
32630
Structure & Mods
synthetic linear peptide [Linear]
noncanonical stereochemical modification [Modified]
unspecified non-canonical residue at 24
Bio-Activity Profile
Hemolytic
human red blood cells
23 % hemolysis at 100 μM
Hemolysis
PMID12450326 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/12450326/
RECORD: Rec_0421206 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Magainin
32630
Structure & Mods
synthetic linear peptide [Linear]
noncanonical stereochemical modification [Modified]
unspecified non-canonical residue at 24
Bio-Activity Profile
Antimicrobial Antibacterial
Escherichia coli IFO 12734
27 μg/mL
MIC
PMID12450326 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/12450326/