Peptide Database

Peptide NameProgonadoliberin-2

Function Ontology

Hormonal / Endocrine ▸ Hormone peptide

Reproductive biology ▸ Reproductive modulation

Standard StatusStandard

Sequence Length62 amino acids

Chemical FormulaC317H505N97O94S2

DescriptionStandard

        QHWSHGWYPGGKRELDSFGTSEISEEIKLCEAGECSYLRPQRRSVLRNIILDALARELQKRK
    

Molecular Weight7243.12 Da

Isoelectric Point (pI)8.76

Net Charge (pH 7.0)1.93

Net Charge (pH 7.4) 1.58

Charge Density (pH 7.0) 0.0311

GRAVY Index-0.84

Hydrophobic Moment 0.72

Boman Index-0.22

Instability Index91.57

Aliphatic Index 78.71

Aromaticity 0.0806

Extinction Coeff. Reduced 13980.00

Extinction Coeff. Oxidized 14105.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 3137.29

LogP -30.89

H-bond Donors 114.0

H-bond Acceptors 100.0

Rotatable Bonds 247.0

Heavy Atoms 510.0

Ring Count 11.0

Amide Bonds 65.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0382865 VERIFIED: YES

Provenance & Taxonomy

OrganismDicentrarchus labrax [Animal]

FamilyProgonadoliberin

Tax ID13489

Structure & Mods

Configlinear peptide [Linear]

Chiralitynoncanonical stereochemical modification [Modified]

N-TermPyroglutamate

Other Mods10:Glycine amide

Bio-Activity Profile

Function

Hormone Endocrine Reproductive regulator

Half-LifeMammalian: 0.8 hour; Yeast: 10 min; E. coli: >10 hour