Peptide Database

Peptide Namebeta-Defensin-3

Function Ontology

Antimicrobial

Standard StatusStandard

Sequence Length45 amino acids

Chemical FormulaC217H379N75O59S6

DescriptionStandard

        GIINTLQKYYCRVRGGRCALLSCLPKEEQIGKCSTRGRKCCRRKK
    

Molecular Weight5175.19 Da

Isoelectric Point (pI)10.08

Net Charge (pH 7.0)10.70

Net Charge (pH 7.4) 10.39

Charge Density (pH 7.0) 0.2377

GRAVY Index-0.71

Hydrophobic Moment 0.63

Boman Index-0.36

Instability Index53.13

Aliphatic Index 69.33

Aromaticity 0.0444

Extinction Coeff. Reduced 2980.00

Extinction Coeff. Oxidized 3355.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 2249.60

LogP -25.63

H-bond Donors 89.0

H-bond Acceptors 76.0

Rotatable Bonds 183.0

Heavy Atoms 357.0

Ring Count 3.0

Amide Bonds 47.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0280889 VERIFIED: NO

Provenance & Taxonomy

OrganismPresbytis melalophos [Animal]; Presbytis obscurus [Animal]; Presbytis cristata [Animal]

FamilyDefensin

Structure & Mods

Configdisulfide-constrained cyclic peptide [Cyclic]

Chiralitycanonical L-amino-acid peptide [L]

Disulfide11-40; 18-33; 23-41

Bio-Activity Profile

Function

Antimicrobial