Peptide Database

Peptide NamePhylloseptin-S1 (PLS-S1) (Phylloseptin-1) (PSN-1)

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive

Antimicrobial ▸ Anti-biofilm ▸ Biofilm inhibition

Antimicrobial ▸ Antibiotic activity

Antimicrobial ▸ Antifungal

Antiparasitic ▸ General antiparasitic ▸ Antiparasitic

Immunology ▸ Innate immune defense ▸ Host defense peptide ▸ Defense peptide

Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic

Toxicity / Safety ▸ Cytolysis / cell lysis ▸ Cytolytic activity

Standard StatusStandard

Sequence Length66 amino acids

Chemical FormulaC339H537N85O106S2

DescriptionStandard

        MAFLKKSLFLVLFLGLVSLSICEEEKRETEEEEHDQEEDDKSEEKRFLSLIPHIVSGVASIAKHFG
    

Molecular Weight7563.53 Da

Isoelectric Point (pI)4.80

Net Charge (pH 7.0)-7.22

Net Charge (pH 7.4) -7.63

Charge Density (pH 7.0) -0.1093

GRAVY Index-0.22

Hydrophobic Moment 0.67

Boman Index0.01

Instability Index67.49

Aliphatic Index 98.94

Aromaticity 0.0758

Extinction Coeff. Reduced 0.00

Extinction Coeff. Oxidized 0.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 3076.42

LogP -23.92

H-bond Donors 106.0

H-bond Acceptors 104.0

Rotatable Bonds 265.0

Heavy Atoms 532.0

Ring Count 9.0

Amide Bonds 66.0

3D PDB MODEL

Drag to rotate. Click a residue or atom to inspect it; the selected residue is highlighted in amber in the current view mode. Use the buttons to zoom.

2D CHEMICAL STRUCTURE

Drag to move

Drag to move. Use the buttons to zoom.

RECORD: Rec_0090598 VERIFIED: YES

Provenance & Taxonomy

OrganismPhyllomedusa sauvagei [Animal]

FamilyPhylloseptin

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Defense peptide Antimicrobial Antibiotic Antifungal Antibiofilm Antiparasitic Anti-Gram-positive Cytolytic Hemolytic

TargetLeishmania species

RECORD: Rec_0215745 VERIFIED: YES