Peptide Database

Peptide NameCycloviolacin O7

Function Ontology

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Standard StatusStandard

Sequence Length28 amino acids

Chemical FormulaC124H201N31O38S6

DescriptionStandard

        SIPCGESCVFIPCISSVVGCSCKNKVCY
    

Molecular Weight2926.50 Da

Isoelectric Point (pI)7.52

Net Charge (pH 7.0)0.40

Net Charge (pH 7.4) 0.10

Charge Density (pH 7.0) 0.0143

GRAVY Index0.86

Hydrophobic Moment 0.35

Boman Index0.27

Instability Index36.25

Aliphatic Index 83.21

Aromaticity 0.0714

Extinction Coeff. Reduced 1490.00

Extinction Coeff. Oxidized 1865.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 1085.25

LogP -12.75

H-bond Donors 43.0

H-bond Acceptors 45.0

Rotatable Bonds 91.0

Heavy Atoms 199.0

Ring Count 4.0

Amide Bonds 28.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0273207 VERIFIED: YES

Provenance & Taxonomy

OrganismMelicytus ramiflorus [Plant]

FamilyCyclotide

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

-

TargetEscherichia coli TOP10

MethodMex pooled growth assay (OD_ID at 4.5 h; Wald adjusted p-value)