Peptide Database

Peptide NameSHIVA 11[(1-16)ME(2-9)]-COOH

Function Ontology

Anticancer

Antimicrobial

Toxicity / Safety ▸ Cytotoxicity ▸ Cytotoxic

Standard StatusStandard

Sequence Length23 amino acids

Chemical FormulaC123H226N32O24

DescriptionStandard

        FAKKLAKKLKKLAKKLIGAVLKV
    

Molecular Weight2537.31 Da

Isoelectric Point (pI)10.90

Net Charge (pH 7.0)8.75

Net Charge (pH 7.4) 8.53

Charge Density (pH 7.0) 0.3805

GRAVY Index0.28

Hydrophobic Moment 0.80

Boman Index-0.02

Instability Index-19.97

Aliphatic Index 144.35

Aromaticity 0.0435

Extinction Coeff. Reduced 0.00

Extinction Coeff. Oxidized 0.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 937.70

LogP -2.23

H-bond Donors 33.0

H-bond Acceptors 33.0

Rotatable Bonds 97.0

Heavy Atoms 179.0

Ring Count 1.0

Amide Bonds 22.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0399436 VERIFIED: YES

Provenance & Taxonomy

Organismsynthetic construct [Synthetic]

FamilyFLAK / Hecate / Shiva peptide family

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

N-TermNone

C-TermNone

Bio-Activity Profile

Function

Anticancer

TargetH-1299

Activity54.0 μg/mL

MethodLD50 / MTT-MTS assay

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