Peptide Database

Peptide NameDPV3

Function Ontology

Anticancer

Anticancer ▸ Cytotoxic anticancer activity ▸ Cytotoxic

Antimicrobial

Delivery / Targeting ▸ Cell penetration ▸ Cell-penetrating peptide

Delivery / Targeting ▸ Drug delivery vehicle

Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic

Toxicity / Safety ▸ Cytotoxicity ▸ Cytotoxic

Venom / Toxin ▸ General toxin ▸ Cytotoxic

Standard StatusStandard

Sequence Length16 amino acids

Chemical FormulaC88H170N44O23

DescriptionStandard

        RKKRRRESRKKRRRES
    

Molecular Weight2212.57 Da

Isoelectric Point (pI)12.00

Net Charge (pH 7.0)9.76

Net Charge (pH 7.4) 9.55

Charge Density (pH 7.0) 0.6101

GRAVY Index-3.76

Hydrophobic Moment 0.43

Boman Index-1.75

Instability Index229.44

Aliphatic Index 0.00

Aromaticity 0.0000

Extinction Coeff. Reduced 0.00

Extinction Coeff. Oxidized 0.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 1214.16

LogP -15.99

H-bond Donors 49.0

H-bond Acceptors 33.0

Rotatable Bonds 87.0

Heavy Atoms 155.0

Ring Count 0.0

Amide Bonds 15.0

3D PDB MODEL

Drag to rotate. Click a residue or atom to inspect it; the selected residue is highlighted in amber in the current view mode. Use the buttons to zoom.

2D CHEMICAL STRUCTURE

Drag to move

Drag to move. Use the buttons to zoom.

RECORD: Rec_0084436 VERIFIED: YES

Provenance & Taxonomy

OrganismProtein derived [Animal]

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

N-TermCys addition

C-TermNone

Bio-Activity Profile

Function

Antimicrobial Anticancer

TargetNot available

RECORD: Rec_0165264 VERIFIED: YES

Provenance & Taxonomy

OrganismHomo sapiens [Animal]

FamilyDPV

Tax ID9606

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

N-TermCysteine addition

C-TermNone

Bio-Activity Profile

Function

Cell-penetrating peptide Cargo delivery

RECORD: Rec_0283382 VERIFIED: YES

Provenance & Taxonomy

OrganismProtein derived [Animal]

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

N-TermCys addition

C-TermNone

Bio-Activity Profile

Function

Antimicrobial Anticancer Cytotoxic

RECORD: Rec_0296374 VERIFIED: YES

Provenance & Taxonomy

OrganismHomo sapiens [Animal]

FamilyDPV/CAP37-derived

Tax ID9606

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

N-TermCys addition for conjugation

C-TermNone

Other ModsN-term detail: Cys added to N -terminus for conjugation of report

Bio-Activity Profile

Function

Cell-penetrating peptide

TargetHeLa; HCT116; HL-60; K562; Molt4; NIH-3T3; primary hepatocyte cultures

MethodCellular uptake assay

RECORD: Rec_0327715 VERIFIED: YES

Provenance & Taxonomy

OrganismProtein derived [Animal]

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

N-TermCys addition

C-TermNone

Bio-Activity Profile

Function

Antimicrobial Anticancer Hemolytic