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MYP_016312
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Basic Information
Angiotensin I-converting enzyme inhibitor 5
Cardiovascular ▸ Blood pressure regulation ▸ Antihypertensive
Enzyme modulation ▸ Enzyme inhibition ▸ ACE inhibition ▸ ACE inhibitory
Membrane / Ion-channel modulation ▸ Calcium channel modulation ▸ Calcium channel inhibitor
Neurological / Signaling ▸ Neuropeptide activity ▸ Neuropeptide
Other / Curated residual function label ▸ Generic enzyme inhibition annotation
Standard
4 amino acids
C22H26N4O7
Standard
Sequence
YGGY
Physicochemical Analysis
458.46 Da
5.52
-0.24
-0.45
-0.0605
-0.85
0.04
0.37
-4.10
0.00
0.5000
2980.00
2980.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
191.08
-0.99
7.0
7.0
11.0
33.0
2.0
3.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0023146 VERIFIED: YES
Provenance & Taxonomy
Oryza sativa [Plant]; Amaranthus hypochondriacus [Plant]
ACE inhibitory peptide
4530, 28502
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Enzyme inhibitory Neuropeptide ACE inhibitory Antihypertensive
Angiotensin-converting enzyme
PaperBioactive peptides in amaranth (Amaranthus hypochondriacus) seed | PubMed PMID 7765503 PMID7765503;18211015 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/7765503/
RECORD: Rec_0117136 VERIFIED: NO
Provenance & Taxonomy
not reported [other]
ACE-inhibitory peptide
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antihypertensive ACE inhibitory
ACE
3.4 μM
IC50
PaperIntegration of QSAR modelling and QM/MM analysis to investigate functional food peptides with antihypertensive activity
RECORD: Rec_0175892 VERIFIED: YES
Provenance & Taxonomy
not reported [other]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
None
Bio-Activity Profile
Antihypertensive
PaperAHTPDB: a comprehensive platform for analysis and presentation of antihypertensive peptides PMID25392419 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/25392419/
RECORD: Rec_0210309 VERIFIED: YES
Provenance & Taxonomy
not reported [other]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antihypertensive ACE inhibitory
Angiotensin-converting enzyme (ACE)
3.4
IC50
PaperSaito Y., Wanezaki K., Kawato A., Imayasu S.. Structure and activity of angiotensin I converting enzyme inhibitory peptides from sake and sake lees. Biosci. Biotech. Biochem., 58(10), 1767-1771 (1994).
RECORD: Rec_0217688 VERIFIED: YES
Provenance & Taxonomy
Oryza sativa [Plant]; Amaranthus hypochondriacus [Plant]
Angiotensin
4530
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Enzyme inhibitory Neuropeptide ACE inhibitory
Angiotensin-converting enzyme
16.2 μM
IC50
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