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MYP_016273
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Basic Information
Reverse Tachyplesin [C3,7,12,16Del]
Anticancer
Anticancer ▸ Cytotoxic anticancer activity ▸ Cytotoxic
Antimicrobial
Antimicrobial ▸ Antibacterial
Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic
Toxicity / Safety ▸ Cytotoxicity ▸ Cytotoxic
Venom / Toxin ▸ General toxin ▸ Cytotoxic
Standard
13 amino acids
C87H134N30O16
Standard
Sequence
RRRYIGRYVRFWK
Physicochemical Analysis
1856.19 Da
11.84
5.76
5.55
0.4429
-1.45
0.87
-0.67
85.75
52.31
0.3077
8480.00
8480.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
804.29
-4.14
33.0
22.0
60.0
133.0
5.0
12.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0316810 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Tachyplesin
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
Amidation
Bio-Activity Profile
Antimicrobial Anticancer Cytotoxic
PaperPubMed PMID: 28641565 PMID28641565 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/28641565/
RECORD: Rec_0333965 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
synthetic linear peptide [Linear]
mixed L/D amino-acid peptide [Mixed]
Bio-Activity Profile
Cytotoxic
Staphylococcus aureus ATCC 25923
8.09 μM
IC90
PMID28641565 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/28641565/
RECORD: Rec_0340768 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
synthetic linear peptide [Linear]
mixed L/D amino-acid peptide [Mixed]
Bio-Activity Profile
Hemolytic
Sheep erythrocytes
8.4 μM
Hemolysis
PMID28641565 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/28641565/
RECORD: Rec_0348157 VERIFIED: NO
Provenance & Taxonomy
not reported [other]
Structure & Mods
topology not specified [Not included yet]
stereochemistry not specified [Other]
Bio-Activity Profile
Anticancer
RECORD: Rec_0349620 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
synthetic linear peptide [Linear]
mixed L/D amino-acid peptide [Mixed]
Bio-Activity Profile
Antimicrobial Antibacterial
Staphylococcus aureus ATCC 25923
8.4 μM
MIC
PMID28641565 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/28641565/
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