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MYP_016273
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Basic Information
Reverse Tachyplesin [C3,7,12,16Del]
Anticancer
Anticancer ▸ Cytotoxic anticancer activity ▸ Cytotoxic
Antimicrobial
Antimicrobial ▸ Antibacterial
Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic
Toxicity / Safety ▸ Cytotoxicity ▸ Cytotoxic
Venom / Toxin ▸ General toxin ▸ Cytotoxic
Standard
13 amino acids
C87H134N30O16
Standard
Sequence
RRRYIGRYVRFWK
Physicochemical Analysis
1856.19 Da
11.84
5.76
5.55
0.4429
-1.45
0.87
-0.67
85.75
52.31
0.3077
8480.00
8480.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
804.29
-4.14
33.0
22.0
60.0
133.0
5.0
12.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0245751 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Tachyplesin
32630
Structure & Mods
linear peptide [Linear]
mixed L/D amino-acid peptide [Mixed]
None
Amidation
k=D-Lys; w=D-Trp; f=D-Phe; r=D-Arg; v=D-Val; y=D-Tyr; i=D-Ile
Bio-Activity Profile
Antimicrobial Anticancer Cytotoxic
PaperPubMed PMID: 28641565 PMID28641565 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/28641565/
RECORD: Rec_0248514 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Tachyplesin
32630
Structure & Mods
linear peptide [Linear]
mixed L/D amino-acid peptide [Mixed]
None
Amidation
k=D-Lys; w=D-Trp; f=D-Phe; r=D-Arg; v=D-Val; y=D-Tyr; i=D-Ile
Bio-Activity Profile
Antimicrobial Anticancer Hemolytic
PaperPubMed PMID: 28641565 PMID28641565 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/28641565/
RECORD: Rec_0254987 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
synthetic linear peptide [Linear]
mixed L/D amino-acid peptide [Mixed]
Bio-Activity Profile
Cytotoxic
Escherichia coli C25
2.05 μM
IC90
PMID28641565 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/28641565/
RECORD: Rec_0256084 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Tachyplesin
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
Amidation
Bio-Activity Profile
Antimicrobial Anticancer
A549
12100 μM
IC50
PaperPubMed PMID: 28641565 PMID28641565 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/28641565/
RECORD: Rec_0310979 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Tachyplesin
32630
Structure & Mods
linear peptide [Linear]
mixed L/D amino-acid peptide [Mixed]
None
Amidation
k=D-Lys; w=D-Trp; f=D-Phe; r=D-Arg; v=D-Val; y=D-Tyr; i=D-Ile
Bio-Activity Profile
Antimicrobial Anticancer
A549
90.16 μM
IC50
PaperPubMed PMID: 28641565 PMID28641565 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/28641565/
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