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MYP_016261
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Basic Information
Protegrin 1/Neutrophil peptide 1/PG-1 [C6V][C8T][R10x][C13T][C15I]
Antimicrobial
Antimicrobial ▸ Antibacterial
Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic
Venom / Toxin ▸ General toxin ▸ Toxic
not Standard
18 amino acids
-
contains X representing unresolved or non-standard residue
Sequence
RGGRLVYTRXRFTVIVGR
Physicochemical Analysis
0.00 Da
0.00
0.00
0.00
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0.00
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Residue Composition
Amino Acid Composition
Chemical Descriptors
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0197206 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Cathelicidin
32630
Structure & Mods
synthetic linear peptide [Linear]
mixed L/D amino-acid peptide [Mixed]
unspecified non-canonical residue at 10
Bio-Activity Profile
Antimicrobial Antibacterial
Escherichia coli JM109
12.5 μg/mL
MIC
PMID17176094 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/17176094/
RECORD: Rec_0232563 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Cathelicidin
32630
Structure & Mods
synthetic linear peptide [Linear]
mixed L/D amino-acid peptide [Mixed]
unspecified non-canonical residue at 10
Bio-Activity Profile
Antimicrobial Antibacterial
Bacillus subtilis BR151
12.5 μg/mL
MIC
PMID17176094 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/17176094/
RECORD: Rec_0286634 VERIFIED: YES
Provenance & Taxonomy
not reported [other]
Structure & Mods
linear peptide [Linear]
D-residue-containing modified peptide [Mixed]
None
Amidation
p*=amino-functionalized D-proline
Bio-Activity Profile
Toxic Antimicrobial Hemolytic
PaperHemolytik: a database of experimentally determined hemolytic and non-hemolytic peptides PMID24174543 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/24174543/
RECORD: Rec_0342444 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Cathelicidin
32630
Structure & Mods
synthetic linear peptide [Linear]
mixed L/D amino-acid peptide [Mixed]
unspecified non-canonical residue at 10
Bio-Activity Profile
Antimicrobial Antibacterial
Staphylococcus aureus 1206
25 μg/mL
MIC
PMID17176094 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/17176094/
RECORD: Rec_0385870 VERIFIED: YES
Provenance & Taxonomy
not reported [other]
Structure & Mods
linear peptide [Linear]
mixed L/D amino-acid peptide [Mixed]
None
Amidation
p*=amino-functionalized D-proline
Bio-Activity Profile
Antimicrobial
Human erythrocytes
100 μg/mL
Hemolysis
Paperhttps://pubmed.ncbi.nlm.nih.gov/17176094/ PMID17176094 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/17176094/
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