Peptide Database

Peptide NamePutative defensin-1

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibiotic activity

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length91 amino acids

Chemical FormulaC422H682N124O120S8

DescriptionStandard

        MKYFTVLAVIFALVACLAVSSATPAAQDEKFVDGALALKHLEPEVHGRYKRATCDLLSGTGVNHSACAAHCLLRGNRGGYCNSKAVCVCRK
    

Molecular Weight9669.21 Da

Isoelectric Point (pI)8.95

Net Charge (pH 7.0)4.78

Net Charge (pH 7.4) 4.24

Charge Density (pH 7.0) 0.0526

GRAVY Index0.25

Hydrophobic Moment 0.54

Boman Index0.09

Instability Index30.48

Aliphatic Index 91.21

Aromaticity 0.0659

Extinction Coeff. Reduced 4470.00

Extinction Coeff. Oxidized 4845.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 3884.00

LogP -40.66

H-bond Donors 144.0

H-bond Acceptors 137.0

Rotatable Bonds 317.0

Heavy Atoms 674.0

Ring Count 12.0

Amide Bonds 94.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0023703 VERIFIED: NO

Provenance & Taxonomy

OrganismHaematobia irritans [Animal]

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Antibiotic Non-hemolytic Non-ribosomal