Peptide Database

Peptide NameEndolysin (EC 3.5.1.28) (N-acetylmuramoyl-L-alanine amidase)

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Bacteriolytic activity ▸ Bacteriolytic enzyme

Enzyme / Catalytic activity ▸ Hydrolase

Toxicity / Safety ▸ Cytolysis / cell lysis ▸ Cytolytic activity

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length151 amino acids

Chemical FormulaC737H1160N214O212S7

DescriptionStandard

        MAKVQFKTRSVTNAIFVHCSATKAGMDIGLREIRQWHKEQGWLDVGYHFIIRRDGTVEEGRPVDAVGSHVKDWNSTSVGICLVGGIDDAGKFKANFTPSQMHSLKVKLAEMQALYPGAAVKAHHDVAAKACPSFDLQRWIKTGELVTSDRG
    

Molecular Weight16634.86 Da

Isoelectric Point (pI)9.05

Net Charge (pH 7.0)4.09

Net Charge (pH 7.4) 3.44

Charge Density (pH 7.0) 0.0271

GRAVY Index-0.26

Hydrophobic Moment 0.75

Boman Index0.01

Instability Index35.68

Aliphatic Index 78.15

Aromaticity 0.0795

Extinction Coeff. Reduced 24980.00

Extinction Coeff. Oxidized 25105.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 6833.50

LogP -68.20

H-bond Donors 242.0

H-bond Acceptors 230.0

Rotatable Bonds 555.0

Heavy Atoms 1170.0

Ring Count 27.0

Amide Bonds 159.0

3D PDB MODEL

Drag to rotate. Click a residue or atom to inspect it; the selected residue is highlighted in amber in the current view mode. Use the buttons to zoom.

2D CHEMICAL STRUCTURE

Drag to move

Drag to move. Use the buttons to zoom.

RECORD: Rec_0346473 VERIFIED: NO

Provenance & Taxonomy

OrganismErwinia phage pEp_SNUABM_11 [Virus]

FamilyN-acetylmuramoyl-L-alanine amidase 2

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Bacteriolytic enzyme Hydrolase Cytolytic Non-hemolytic