Peptide Database

Peptide NameLantibiotic nisin-A (Putative SpaS protein)

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibiotic activity

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length57 amino acids

Chemical FormulaC256H413N69O91S8

DescriptionStandard

        MLKDFDLNLKMETGSSDDKEPRITSVAYCTPGCLTGELCGSSECGLTRSCTNTWLCS
    

Molecular Weight6169.95 Da

Isoelectric Point (pI)4.51

Net Charge (pH 7.0)-3.55

Net Charge (pH 7.4) -3.87

Charge Density (pH 7.0) -0.0622

GRAVY Index-0.26

Hydrophobic Moment 0.40

Boman Index-0.02

Instability Index51.16

Aliphatic Index 61.58

Aromaticity 0.0526

Extinction Coeff. Reduced 6990.00

Extinction Coeff. Oxidized 7365.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 2581.02

LogP -33.60

H-bond Donors 97.0

H-bond Acceptors 96.0

Rotatable Bonds 204.0

Heavy Atoms 424.0

Ring Count 6.0

Amide Bonds 58.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0424079 VERIFIED: NO

Provenance & Taxonomy

OrganismClostridium perfringens [Bacterium]

FamilyLantibiotic

Tax ID1502

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Bacteriocin Lantibiotic Non-hemolytic Non-ribosomal