Peptide Database

Peptide NameTumor necrosis factor ligand superfamily member 12, secreted form

Function Ontology

Anticancer ▸ tumor necrosis factor family

Immunology ▸ Immune modulation ▸ Cytokine modulation

Regulatory peptide ▸ Cell signaling / Growth factor signaling ▸ Growth factor activity

Wound healing/Regeneration ▸ Angiogenesis modulation ▸ Angiogenic

Standard StatusStandard

Sequence Length156 amino acids

Chemical FormulaC775H1220N224O214S3

DescriptionStandard

        SAPKGRKTRARRAIAAHYEVHPRPGQDGAQAGVDGTVSGWEEARINSSSPLRYNRQIGEFIVTRAGLYYLYCQVHFDEGKAVYLKLDLLVDGVLALRCLEEFSATAASSLGPQLRLCQVSGLLALRPGSSLRIRTLPWAHLKAAPFLTYFGLFQVH
    

Molecular Weight17195.54 Da

Isoelectric Point (pI)9.62

Net Charge (pH 7.0)6.88

Net Charge (pH 7.4) 6.34

Charge Density (pH 7.0) 0.0441

GRAVY Index-0.09

Hydrophobic Moment 0.70

Boman Index0.04

Instability Index34.51

Aliphatic Index 95.13

Aromaticity 0.0962

Extinction Coeff. Reduced 21430.00

Extinction Coeff. Oxidized 21555.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 6996.11

LogP -65.72

H-bond Donors 251.0

H-bond Acceptors 229.0

Rotatable Bonds 557.0

Heavy Atoms 1216.0

Ring Count 30.0

Amide Bonds 164.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0063229 VERIFIED: YES

Provenance & Taxonomy

OrganismHomo sapiens [Animal]

Familytumor necrosis factor family

Tax ID9606; 0

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Disulfide98-117

Bio-Activity Profile

Function

Cytokine Growth factor tumor necrosis factor family Angiogenic