Peptide Database

Peptide NameLantibiotic

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive

Antimicrobial ▸ Antibiotic activity

Standard StatusStandard

Sequence Length60 amino acids

Chemical FormulaC263H436N84O86S6

DescriptionStandard

        MNNQFNLKSKSANVSGSKGNNLETRITSKSLCTPGCKTGALQTCFAKTATCHCSGHVHTK
    

Molecular Weight6343.18 Da

Isoelectric Point (pI)9.60

Net Charge (pH 7.0)6.71

Net Charge (pH 7.4) 6.26

Charge Density (pH 7.0) 0.1118

GRAVY Index-0.54

Hydrophobic Moment 0.44

Boman Index-0.10

Instability Index15.29

Aliphatic Index 48.83

Aromaticity 0.0333

Extinction Coeff. Reduced 0.00

Extinction Coeff. Oxidized 250.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 2786.98

LogP -43.12

H-bond Donors 102.0

H-bond Acceptors 102.0

Rotatable Bonds 216.0

Heavy Atoms 439.0

Ring Count 6.0

Amide Bonds 67.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0155233 VERIFIED: NO

Provenance & Taxonomy

OrganismStaphylococcus capitis [Bacterium]

FamilyLantibiotic

Structure & Mods

Configthioether-cyclized lantibiotic scaffold [Cyclic]

Chiralitypost-translationally modified ribosomal peptide [Modified]

Other ModsLanthionine/methyllanthionine-type thioether crosslinks are implied by the lantibiotic annotation

Bio-Activity Profile

Function

Antibiotic Antimicrobial Bacteriocin Lantibiotic Anti-Gram-positive

TargetGram-positive bacteria