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MYP_016223
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Basic Information
Ocellatin-PT3
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative
Antiparasitic ▸ Antiprotozoal
Antiparasitic ▸ General antiparasitic ▸ Antiparasitic
Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic
Standard
25 amino acids
C115H201N31O32
Standard
Sequence
GVIDIIKGAGKDLIAHAIGKLAEKV
Physicochemical Analysis
2530.01 Da
8.44
0.85
0.59
0.0339
0.59
0.61
0.27
-17.57
148.40
0.0000
0.00
0.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
1006.38
-6.43
34.0
34.0
90.0
178.0
1.0
24.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0014667 VERIFIED: YES
Provenance & Taxonomy
Leptodactylus pustulatus [Animal]
Ocellatin
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Antiparasitic Antiprotozoal
Leishmania infantum MHOM/MA/67/ITMAP-263
34 μg/mL
IC50
PMID26107622;27463422;29308671 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/26107622/
RECORD: Rec_0016624 VERIFIED: YES
Provenance & Taxonomy
Skin Secretion,dorsal,Leptodactylus pustulatus [other]
Structure & Mods
topology not specified [Not included yet]
stereochemistry not specified [Other]
Bio-Activity Profile
Antiparasitic
PMID26107622;27463422 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/26107622/
RECORD: Rec_0042678 VERIFIED: YES
Provenance & Taxonomy
Leptodactylus pustulatus [Animal]
Ocellatin
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Antiparasitic Antiprotozoal
Escherichia coli ATCC 25922
800 μg/mL
MIC
PMID26107622;27463422;29308671 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/26107622/
RECORD: Rec_0083043 VERIFIED: YES
Provenance & Taxonomy
Leptodactylus pustulatus [Animal]
Ocellatin
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Antiparasitic Antiprotozoal
Pseudomonas aeruginosa PA006
16 μg/mL
MIC
PMID26107622;27463422;29308671 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/26107622/
RECORD: Rec_0107768 VERIFIED: YES
Provenance & Taxonomy
Leptodactylus pustulatus [Animal]
Ocellatin
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Hemolytic
Human erythrocytes (1% Hemolysis at 800 microg/ml, Mouse fibroblasts NIH 3T3 (- at NA
800 μg/mL
Hemolysis
PMID26107622;27463422;29308671 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/26107622/
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