Peptide Database

Peptide NameBeta-defensin

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibiotic activity

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length86 amino acids

Chemical FormulaC408H666N124O110S11

DescriptionStandard

        RKLLLLVCTALGFLVTPASGGGTSCGHKVPGHCRMHCGPREKTMFTCDRNKQCCVKDFFIPEPMVPPPVHRPKKPCRTGTASQTQK
    

Molecular Weight9421.13 Da

Isoelectric Point (pI)9.65

Net Charge (pH 7.0)10.03

Net Charge (pH 7.4) 9.49

Charge Density (pH 7.0) 0.1166

GRAVY Index-0.37

Hydrophobic Moment 0.53

Boman Index-0.07

Instability Index46.62

Aliphatic Index 55.47

Aromaticity 0.0465

Extinction Coeff. Reduced 0.00

Extinction Coeff. Oxidized 500.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 3687.29

LogP -40.44

H-bond Donors 134.0

H-bond Acceptors 135.0

Rotatable Bonds 302.0

Heavy Atoms 653.0

Ring Count 18.0

Amide Bonds 89.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0049876 VERIFIED: NO

Provenance & Taxonomy

OrganismSus scrofa [Animal]

FamilyDefensin

Tax ID9823

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Defensin Non-hemolytic Non-ribosomal

MethodQualitative functional evidence