Peptide Database

Peptide NamePUIA_WHEAT

Function Ontology

Cardiovascular ▸ Blood pressure regulation ▸ Antihypertensive

Enzyme modulation ▸ Enzyme inhibition ▸ ACE inhibition ▸ ACE inhibitory

Neurological / Signaling ▸ Signaling peptide

Other / Curated residual function label ▸ Generic enzyme inhibition annotation

Standard StatusStandard

Sequence Length148 amino acids

Chemical FormulaC728H1124N202O204S13

DescriptionStandard

        GSIQGDLGGIFGFQRDRASKVIQEAKNLPPRCNQGPPCNIPGTIGYYWMKALFLIGLLALVASTAFAQYSEVVGSYDVAGGGGAQQCPVETKLNSCRNYLLDRCSTMKDFPVTWRWWKWWKGGCQELLGECCSRLGQMPPQCRCNIIQ
    

Molecular Weight16386.79 Da

Isoelectric Point (pI)8.72

Net Charge (pH 7.0)4.67

Net Charge (pH 7.4) 4.29

Charge Density (pH 7.0) 0.0315

GRAVY Index-0.17

Hydrophobic Moment 0.58

Boman Index0.07

Instability Index42.46

Aliphatic Index 75.14

Aromaticity 0.1081

Extinction Coeff. Reduced 40450.00

Extinction Coeff. Oxidized 41075.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 6503.66

LogP -63.10

H-bond Donors 232.0

H-bond Acceptors 222.0

Rotatable Bonds 529.0

Heavy Atoms 1147.0

Ring Count 31.0

Amide Bonds 164.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0019563 VERIFIED: YES

Provenance & Taxonomy

OrganismTriticum aestivum [Plant]

Tax ID4565

Structure & Mods

Configdisulfide-constrained cyclic peptide [Cyclic]

Chiralitycanonical L-amino-acid peptide [L]

Disulfidedisulfide bond reported, sites not specified

Bio-Activity Profile

Function

Signaling Enzyme inhibitory ACE inhibitory Antihypertensive

TargetAngiotensin-converting enzyme