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MYP_016060
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Basic Information
Endothelin-3
Cardiovascular
Cardiovascular ▸ Vascular tone modulation ▸ Vasoactive peptide
Cardiovascular ▸ Vascular tone modulation ▸ Vasoconstrictor activity
Enzyme modulation ▸ Enzyme inhibition ▸ ACE inhibition ▸ ACE inhibitory
Hormonal / Endocrine ▸ Hormone peptide
Immunology ▸ Immune modulation ▸ Immunomodulatory activity
Neurological / Signaling ▸ Neuromodulation
Neurological / Signaling ▸ Neuromuscular and muscle activity ▸ Myotropic activity
Neurological / Signaling ▸ Neuropeptide activity ▸ Neuropeptide
Regulatory peptide ▸ Biological modulation
Regulatory peptide ▸ Biological regulation
Regulatory peptide ▸ Cell-cell communication
Standard
21 amino acids
C121H172N26O33S4
Standard
Sequence
CTCFTYKDKECVYYCHLDIIW
Physicochemical Analysis
2647.07 Da
5.38
-1.19
-1.51
-0.0568
0.10
0.26
0.13
56.15
69.52
0.2381
9970.00
10220.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
954.88
-3.78
38.0
37.0
81.0
184.0
7.0
20.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0224593 VERIFIED: NO
Provenance & Taxonomy
Rattus norvegicus [Animal]
Endothelin
10116
Structure & Mods
disulfide-constrained peptide [Cyclic]
canonical L-amino-acid peptide [L]
1-15; 3-11
Bio-Activity Profile
Hormone Endocrine Neuropeptide Neuromodulator Vasoactive Vasoconstrictor Cardiovascular Growth regulation Development regulation Myotropic Receptor modulation Immunomodulatory ACE inhibitory
Mammalian: 1.2 hour; Yeast: >20 hour; E. coli: >10 hour
RECORD: Rec_0238083 VERIFIED: NO
Provenance & Taxonomy
Mus musculus [Animal]
Endothelin/sarafotoxin
10090
Structure & Mods
disulfide-constrained cyclic peptide [Cyclic]
canonical L-amino-acid peptide [L]
1-15; 3-11
Bio-Activity Profile
Vasoactive Hormone
Evidence URLhttps://www.uniprot.org/uniprotkb/EDN3_MOUSE/entry
RECORD: Rec_0240640 VERIFIED: NO
Provenance & Taxonomy
Canis familiaris [Animal]
Endothelin/sarafotoxin
9615
Structure & Mods
disulfide-constrained cyclic peptide [Cyclic]
canonical L-amino-acid peptide [L]
1-15; 3-11
Bio-Activity Profile
Vasoactive Hormone
Evidence URLhttps://www.uniprot.org/uniprotkb/EDN3_CANFA/entry
RECORD: Rec_0252611 VERIFIED: NO
Provenance & Taxonomy
Oryctolagus cuniculus [Animal]
Endothelin/sarafotoxin
9986
Structure & Mods
disulfide-constrained cyclic peptide [Cyclic]
canonical L-amino-acid peptide [L]
1-15; 3-11
Bio-Activity Profile
Vasoactive Hormone
Evidence URLhttps://www.uniprot.org/uniprotkb/EDN3_RABIT/entry
RECORD: Rec_0252783 VERIFIED: NO
Provenance & Taxonomy
Rattus norvegicus [Animal]; Homo sapiens [Animal]; Mus musculus [Animal]; Oryctolagus cuniculus [Animal]
10116, 9606, 10090, 9986
Structure & Mods
disulfide-constrained cyclic peptide [Cyclic]
canonical L-amino-acid peptide [L]
1-15; 3-11
Bio-Activity Profile
Neuropeptide
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