Peptide Database

Peptide NameGlucagon-like peptide 2

Function Ontology

Hormonal / Endocrine ▸ Hormone peptide

Metabolic

Neurological / Signaling ▸ Neuropeptide activity ▸ Neuropeptide

Regulatory peptide ▸ Biological regulation

Standard StatusStandard

Sequence Length32 amino acids

Chemical FormulaC158H246N48O50S3

DescriptionStandard

        HSDGSFTNDMNVMLDRMSAKNFLEWLKQQGRG
    

Molecular Weight3714.13 Da

Isoelectric Point (pI)6.76

Net Charge (pH 7.0)-0.15

Net Charge (pH 7.4) -0.41

Charge Density (pH 7.0) -0.0046

GRAVY Index-0.88

Hydrophobic Moment 0.63

Boman Index-0.16

Instability Index18.93

Aliphatic Index 48.75

Aromaticity 0.0938

Extinction Coeff. Reduced 5500.00

Extinction Coeff. Oxidized 5500.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 1631.30

LogP -18.84

H-bond Donors 56.0

H-bond Acceptors 54.0

Rotatable Bonds 128.0

Heavy Atoms 259.0

Ring Count 5.0

Amide Bonds 36.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0081362 VERIFIED: NO

Provenance & Taxonomy

OrganismPetromyzon marinus [Animal]

FamilyGlucagon-like peptide

Tax ID7757

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Hormone Endocrine Metabolic regulation Physiological regulation

Half-LifeMammalian: 3.5 hour; Yeast: 10 min; E. coli: >10 hour

RECORD: Rec_0134651 VERIFIED: NO

Provenance & Taxonomy

OrganismPetromyzon marinus [Animal]

FamilyGlucagon

Tax ID7757

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Hormone Metabolic

RECORD: Rec_0346048 VERIFIED: YES

Provenance & Taxonomy

Organismnot reported [other]

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Neuropeptide

Paper数据库级溯源文献：Wang Y, Wang M, Yin S, et al. NeuroPep: a comprehensive resource of neuropeptides. Database (Oxford). 2015:bav038. PMID 25931458; Bin Y, Zhang W, Tang W, et al. Prediction of Neuropeptides from Sequence Information Using Ensemble Classifier and Hybrid Features. J Proteome Res. 2020;19(9):3732-3740. PMID 32786686. PMID25931458;32786686 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/25931458/