MYP_015981
Temporin-PMb
Anticancer
Antimicrobial
Standard
13 amino acids
C78H112N14O15
Standard
FLPFLGKLFSGIF
1485.81 Da
8.75
0.76
0.55
0.0584
1.54
0.48
0.67
19.27
120.00
0.3077
0.00
0.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Amino Acid Composition
449.98
1.26
15.0
16.0
45.0
107.0
5.0
12.0
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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RECORD: Rec_0282522
VERIFIED: YES
Provenance & Taxonomy
Lithobates palmipes [Animal]
Temporin
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Amidation
isolated from skin secretion via RP-HPLC. Sequence analysis: APD analysis reveals that this sequence is similar (92.31%) to Temporin-PMa F: 31%, L: 23%. GRAVY: 1.538, mol Wt: 1485.832, mol formula: C78H112N14O15, mol ex coeff: 0. It differs from Temporin-PMa only at a single position, F for this peptide and L for AP3610 (PMa). Chemical modification: C-terminal amidation
Bio-Activity Profile
Antimicrobial
Anticancer
also MDR MIC>128 uM AMP-resistant?, and Staphylococcus aureus ATCC 25923
8 μM
MIC
RECORD: Rec_0293162
VERIFIED: YES
Provenance & Taxonomy
Lithobates palmipes [Animal]
Temporin
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Amidation
isolated from skin secretion via RP-HPLC. Sequence analysis: APD analysis reveals that this sequence is similar (92.31%) to Temporin-PMa F: 31%, L: 23%. GRAVY: 1.538, mol Wt: 1485.832, mol formula: C78H112N14O15, mol ex coeff: 0. It differs from Temporin-PMa only at a single position, F for this peptide and L for AP3610 (PMa). Chemical modification: C-terminal amidation
Bio-Activity Profile
Antimicrobial
Anticancer
Escherichia coli ATCC 25922
16 μM
MIC
RECORD: Rec_0313836
VERIFIED: YES
Provenance & Taxonomy
Lithobates palmipes [Animal]
Temporin
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Amidation
isolated from skin secretion via RP-HPLC. Sequence analysis: APD analysis reveals that this sequence is similar (92.31%) to Temporin-PMa F: 31%, L: 23%. GRAVY: 1.538, mol Wt: 1485.832, mol formula: C78H112N14O15, mol ex coeff: 0. It differs from Temporin-PMa only at a single position, F for this peptide and L for AP3610 (PMa). Chemical modification: C-terminal amidation
Bio-Activity Profile
Antimicrobial
Anticancer
highly hemolytic above 64 uM
32-64 μM
HC50
RECORD: Rec_0318109
VERIFIED: YES
Provenance & Taxonomy
Lithobates palmipes [Animal]
Temporin
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Amidation
isolated from skin secretion via RP-HPLC. Sequence analysis: APD analysis reveals that this sequence is similar (92.31%) to Temporin-PMa F: 31%, L: 23%. GRAVY: 1.538, mol Wt: 1485.832, mol formula: C78H112N14O15, mol ex coeff: 0. It differs from Temporin-PMa only at a single position, F for this peptide and L for AP3610 (PMa). Chemical modification: C-terminal amidation
Bio-Activity Profile
Antimicrobial
Anticancer
MCF7 cancer cells
24.1 μM
IC50
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