Peptide Database

Peptide NameAbciximab

Function Ontology

Hemostasis ▸ Anticoagulant activity

Immunology ▸ Immune modulation ▸ Immunomodulatory activity

Standard StatusStandard

Sequence Length225 amino acids

Chemical FormulaC1081H1659N275O336S8

DescriptionStandard

        EVQLQQSGTVLARPGASVKMSCEASGYTFTNYWMHWVKQRPGQGLEWIGAIYPGNSDTSYIQKFKGKAKLTAVTSTTSVYMELSSLTNEDSAVYYCTLYDGYYVFAYWGQGTLVTVSAASTKGPSVFPLAPSSKSTSGGTAALGCLVKDYFPEPVTVSWNSGALTSGVHTFPAVLQSSGLYSLSSVVTVPSSSLGTQTYICNVNHKPSNTKVDKKVEPKSCDKTH
    

Molecular Weight24139.90 Da

Isoelectric Point (pI)8.71

Net Charge (pH 7.0)4.13

Net Charge (pH 7.4) 3.63

Charge Density (pH 7.0) 0.0184

GRAVY Index-0.17

Hydrophobic Moment 0.51

Boman Index0.11

Instability Index43.07

Aliphatic Index 69.69

Aromaticity 0.1111

Extinction Coeff. Reduced 48360.00

Extinction Coeff. Oxidized 48610.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0316653 VERIFIED: NO

Provenance & Taxonomy

OrganismHomo sapiens [Animal]; Mus musculus [Animal]

FamilyMonoclonal antibody

Tax ID9606; 10090

Structure & Mods

Configsingle-chain therapeutic peptide/protein [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Immunomodulatory Anticoagulant

Half-Lifeinitial half-life of less than 10 minutes and a second phase half-life of about 30 minutes