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MYP_015905
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Basic Information
Malabar grouper piscidin 1 (EmPis-1L)
Anticancer
Anticancer ▸ Cytotoxic anticancer activity ▸ Cytotoxic
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive
Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic
Toxicity / Safety ▸ Cytotoxicity ▸ Cytotoxic
Venom / Toxin ▸ General toxin ▸ Cytotoxic
Standard
45 amino acids
C242H379N73O61S
Standard
Sequence
FIFHIIKGLFHAGKMIHGLVTRRRHGVEELQDLDQRAFEREKAFA
Physicochemical Analysis
5319.12 Da
9.69
2.12
1.70
0.0471
-0.28
0.59
-0.05
65.88
91.11
0.1111
0.00
0.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
2176.21
-15.13
77.0
68.0
183.0
377.0
9.0
46.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0006380 VERIFIED: YES
Provenance & Taxonomy
Epinephelus malabaricus [Animal]
Pleurocidin
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative
Vibrio parahaemolyticus OS4
PMID30032476 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/30032476/
RECORD: Rec_0153960 VERIFIED: YES
Provenance & Taxonomy
Epinephelus coioides,Epinephelus malabaricus [Animal]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
None
Bio-Activity Profile
Antimicrobial Anticancer Hemolytic
Rabbit erythrocytes
47 %
Hemolysis
PaperPubMed PMID: 30032476 PMID30032476 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/30032476/
RECORD: Rec_0156437 VERIFIED: YES
Provenance & Taxonomy
Epinephelus malabaricus [Animal]
Pleurocidin
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative
VBNC state of Escherichia coli O157
PMID30032476 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/30032476/
RECORD: Rec_0218953 VERIFIED: YES
Provenance & Taxonomy
Epinephelus malabaricus [Animal]
Pleurocidin
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative
Staphylococcus aureus
PMID30032476 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/30032476/
RECORD: Rec_0235352 VERIFIED: YES
Provenance & Taxonomy
Epinephelus coioides,Epinephelus malabaricus [Animal]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
None
Bio-Activity Profile
Antimicrobial Anticancer
73.5 %
Cytotoxicity
PaperPubMed PMID: 30032476 PMID30032476 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/30032476/
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