Peptide Database

Peptide NameAngiotensin I-converting enzyme inhibitory peptide 18

Function Ontology

Cardiovascular ▸ Blood pressure regulation ▸ Antihypertensive

Enzyme modulation ▸ Enzyme inhibition ▸ ACE inhibition ▸ ACE inhibitory

Other / Curated residual function label ▸ Generic enzyme inhibition annotation

Standard StatusStandard

Sequence Length4 amino acids

Chemical FormulaC17H29N5O6

DescriptionStandard

        QVGP
    

Molecular Weight399.44 Da

Isoelectric Point (pI)5.53

Net Charge (pH 7.0)-0.24

Net Charge (pH 7.4) -0.44

Charge Density (pH 7.0) -0.0600

GRAVY Index-0.33

Hydrophobic Moment 0.41

Boman Index0.21

Instability Index-32.58

Aliphatic Index 72.50

Aromaticity 0.0000

Extinction Coeff. Reduced 0.00

Extinction Coeff. Oxidized 0.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 184.92

LogP -2.09

H-bond Donors 5.0

H-bond Acceptors 6.0

Rotatable Bonds 10.0

Heavy Atoms 28.0

Ring Count 1.0

Amide Bonds 4.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0126049 VERIFIED: YES

Provenance & Taxonomy

OrganismSus scrofa [Animal]

FamilyAngiotensin

Tax ID9823

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Enzyme inhibitory ACE inhibitory

TargetAngiotensin-I converting enzyme

Activity160.80±1.29 μM

MethodIC50

RECORD: Rec_0133614 VERIFIED: YES

Provenance & Taxonomy

Organismnot reported [other]

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antihypertensive ACE inhibitory

TargetAngiotensin-converting enzyme (ACE)

Activity160.8

MethodIC50