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MYP_015734
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Basic Information
Psyle E
Anticancer
Anticancer ▸ Cytotoxic anticancer activity ▸ Cytotoxic
Antimicrobial
Antimicrobial ▸ Antibacterial
Toxicity / Safety ▸ Cytotoxicity ▸ Cytotoxic
Venom / Toxin ▸ General toxin ▸ Cytotoxic
Standard
31 amino acids
C139H227N37O42S6
Standard
Sequence
GVIPCGESCVFIPCISSVLGCSCKNKVCYRD
Physicochemical Analysis
3280.90 Da
7.77
0.70
0.41
0.0227
0.65
0.35
0.18
30.99
87.74
0.0645
1490.00
1865.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
1251.52
-13.87
49.0
49.0
104.0
224.0
4.0
31.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0127796 VERIFIED: NO
Provenance & Taxonomy
not reported [other]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Anticancer
PaperAntiCP 2.0: an updated model for predicting anticancer peptides (benchmark provenance; exact sequence-level experiment paper unresolved here) | https://pubmed.ncbi.nlm.nih.gov/32770192/
RECORD: Rec_0167276 VERIFIED: YES
Provenance & Taxonomy
Psychotria leptothyrsa [Plant]
Cyclotide
Structure & Mods
head-to-tail cyclic peptide [Cyclic]
canonical L-amino-acid peptide [L]
multiple disulfide bonds reported, sites not specified
Bio-Activity Profile
Anticancer Cytotoxic
Human histiocytic lymphoma U-937/GTB
0.76 μM
IC50
PaperPubMed PMID 20564026 | PubMed PMID 20575510 PMID20564026;20575510 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/20564026/
RECORD: Rec_0183217 VERIFIED: YES
Provenance & Taxonomy
not reported [other]
Structure & Mods
cyclic peptide [Cyclic]
canonical L-amino-acid peptide [L]
None
None
Bio-Activity Profile
Antimicrobial
PaperAPD2: the updated antimicrobial peptide database and its application in peptide design PMID18957441 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/18957441/
RECORD: Rec_0192266 VERIFIED: YES
Provenance & Taxonomy
Psychotria leptothyrsa [Animal]
Cyclotide
Structure & Mods
head-to-tail cyclic peptide [Cyclic]
canonical L-amino-acid peptide [L]
None
None
Disulfide bond(s) reported
Bio-Activity Profile
Anticancer
PaperPubMed PMID: 20575512 PMID20575512 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/20575512/
RECORD: Rec_0207557 VERIFIED: YES
Provenance & Taxonomy
Psychotria leptothyrsa [Plant]
Psychotria leptothyrsa
Structure & Mods
topology not specified [Not included yet]
canonical L-amino-acid peptide [L]
None
None
Bio-Activity Profile
Antibacterial
PMID20575512;18957441 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/20575512/
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