Peptide Database

Peptide Namemini-M-Conotoxin Reg12l

Function Ontology

Anticancer ▸ Cytotoxic anticancer activity ▸ Cytotoxic

Toxicity / Safety ▸ Cytotoxicity ▸ Cytotoxic

Venom / Toxin ▸ General toxin ▸ Cytotoxic

Venom / Toxin ▸ General toxin ▸ Toxic

Venom / Toxin ▸ General toxin ▸ Toxin

Standard StatusStandard

Sequence Length19 amino acids

Chemical FormulaC84H124N22O20S7

DescriptionStandard

        RCCPMPGCFAGPFCPCCPP
    

Molecular Weight1986.47 Da

Isoelectric Point (pI)7.78

Net Charge (pH 7.0)0.70

Net Charge (pH 7.4) 0.41

Charge Density (pH 7.0) 0.0369

GRAVY Index0.49

Hydrophobic Moment 0.25

Boman Index0.24

Instability Index75.35

Aliphatic Index 5.26

Aromaticity 0.1053

Extinction Coeff. Reduced 0.00

Extinction Coeff. Oxidized 375.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 596.28

LogP -5.47

H-bond Donors 23.0

H-bond Acceptors 28.0

Rotatable Bonds 48.0

Heavy Atoms 133.0

Ring Count 8.0

Amide Bonds 18.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0221151 VERIFIED: NO

Provenance & Taxonomy

OrganismConus regius [Animal]

FamilyConotoxin

Structure & Mods

Configdisulfide-constrained cyclic peptide [Cyclic]

Chiralitycanonical L-amino-acid peptide [L]

Disulfide2-17; 3-14; 8-16

Bio-Activity Profile

Function

Toxin

RECORD: Rec_0334597 VERIFIED: NO

Provenance & Taxonomy

Organismnot reported [other]

Structure & Mods

Configlinear peptide; DSSP H 0.0%, E 10.5%, T 52.6%, C 36.8% [Linear]

Chiralitycanonical L-amino-acid peptide [L]

N-TermNone

C-TermNone

Bio-Activity Profile

Function

Toxic Cytotoxic