Peptide Database

Peptide NameEndolysin (EC 4.2.2.n2) (Lysis protein) (Lysozyme) (Transglycosylase)

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Bacteriolytic activity ▸ Bacteriolytic enzyme

Enzyme / Catalytic activity ▸ Lyase

Toxicity / Safety ▸ Cytolysis / cell lysis ▸ Cytolytic activity

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length156 amino acids

Chemical FormulaC777H1240N220O224S5

DescriptionStandard

        MKLDKNVQRKAFLDMIAYSEGTDNGRQPTKDRGYDVIVGGKLFSDYSKHPGVYVKLNAKLTSSAAGRYQVLEKFAKHYMKQLGLPDFGPASQDKIALQLIRECKALADIDEGRIHEAIHKCRSRWASLPGAGYGQHEQKIEKLIDVFKKAGGVVLD
    

Molecular Weight17407.82 Da

Isoelectric Point (pI)9.35

Net Charge (pH 7.0)6.93

Net Charge (pH 7.4) 6.37

Charge Density (pH 7.0) 0.0444

GRAVY Index-0.50

Hydrophobic Moment 0.75

Boman Index-0.07

Instability Index34.58

Aliphatic Index 83.21

Aromaticity 0.0833

Extinction Coeff. Reduced 15930.00

Extinction Coeff. Oxidized 16055.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 7199.45

LogP -66.68

H-bond Donors 250.0

H-bond Acceptors 241.0

Rotatable Bonds 598.0

Heavy Atoms 1226.0

Ring Count 24.0

Amide Bonds 166.0

3D PDB MODEL

Drag to rotate. Click a residue or atom to inspect it; the selected residue is highlighted in amber in the current view mode. Use the buttons to zoom.

2D CHEMICAL STRUCTURE

Drag to move

Drag to move. Use the buttons to zoom.

RECORD: Rec_0225566 VERIFIED: NO

Provenance & Taxonomy

OrganismEscherichia phage pangalan [Virus]

FamilyGlycosyl hydrolase 24

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Bacteriolytic enzyme Lyase Cytolytic Non-hemolytic