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MYP_015701
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Basic Information
Palustrin-2SIb
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive
Antimicrobial ▸ Antifungal
Standard
36 amino acids
C174H292N48O48S2
Standard
Sequence
GLWNSIKIAGKKLFVNVLDKIRCKVAGGCKTSPDVE
Physicochemical Analysis
3888.60 Da
9.51
3.74
3.50
0.1040
0.04
0.65
0.04
16.76
102.78
0.0556
5500.00
5625.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
1565.61
-13.87
56.0
54.0
134.0
272.0
4.0
37.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0337198 VERIFIED: YES
Provenance & Taxonomy
Odorrana ishikawae [Animal]
Structure & Mods
disulfide-constrained cyclic peptide [Cyclic]
canonical L-amino-acid peptide [L]
None
None
23-29
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative
Staphylococcus aureus (MRSA)
100 μM
MIC
PMID21911019 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/21911019/
RECORD: Rec_0346192 VERIFIED: YES
Provenance & Taxonomy
Odorrana ishikawae [Animal]
Structure & Mods
disulfide-constrained cyclic peptide [Cyclic]
canonical L-amino-acid peptide [L]
None
None
23-29
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative
Staphylococcus aureus
6.3 μM
MIC
PMID21911019 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/21911019/
RECORD: Rec_0379309 VERIFIED: YES
Provenance & Taxonomy
Odorrana ishikawae [Animal]
Palustrin
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative
Staphylococcus aureus
100 μM
MIC
PMID21911019 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/21911019/
RECORD: Rec_0394651 VERIFIED: YES
Provenance & Taxonomy
Odorrana ishikawae [Animal]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
-
Escherichia coli TOP10
Mex pooled growth assay (OD_ID at 4.5 h; Wald adjusted p-value)
PaperKoch P, Schmitt S, Cardner M, Beerenwinkel N, Panke S, Held M. Discovery of antimicrobials by massively parallelized growth assays (Mex). Scientific Reports. 2022;12:4097. doi:10.1038/s41598-022-07755-7 PMID35260685 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/35260685/
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