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MYP_015680
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Basic Information
EtCec1-NH2
Anticancer
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Antifungal
Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic
Toxicity / Safety ▸ Cytotoxicity ▸ Cytotoxic
Standard
40 amino acids
C181H314N56O54
Standard
Sequence
GFLKKIGKKLEGAVQRTRDATIQTIAVAQAAANVAATAKQ
Physicochemical Analysis
4138.77 Da
10.56
4.76
4.55
0.1190
-0.06
0.63
-0.01
5.05
95.50
0.0250
0.00
0.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
1823.09
-21.19
63.0
59.0
145.0
291.0
1.0
44.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0134408 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Antifungal
Salmonella enterica
16 μg/mL
MIC50
PMID32344933 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/32344933/
RECORD: Rec_0170485 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Antifungal
Escherichia coli ATCC 25922
8 μg/mL
MIC
PMID32344933 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/32344933/
RECORD: Rec_0188128 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Antifungal
Escherichia coli D31
4 μg/mL
MIC
PMID32344933 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/32344933/
RECORD: Rec_0189166 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Amidation
Bio-Activity Profile
Cytotoxicity-tested Non-cytotoxic
HepG2 human hepatocellular carcinoma cells
>1655 μg/mL
Cytotoxicity assay (neutral-red uptake / ATP; no effect up to tested limit)
PaperPubMed PMID: 32344933 PMID32344933 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/32344933/
RECORD: Rec_0207128 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Amidation
Bio-Activity Profile
Non-hemolytic Hemolysis-tested
human erythrocytes
>1024 μg/mL
Hemolysis (no hemolysis at highest tested concentration)
PaperPubMed PMID: 32344933 PMID32344933 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/32344933/
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