Peptide Database

Peptide NameUnnamed

Function Ontology

Antimicrobial

Antiviral

Antiviral ▸ Antiviral mechanism ▸ Viral entry inhibition ▸ Entry inhibitor

Standard StatusStandard

Sequence Length48 amino acids

Chemical FormulaC258H402N80O70S2

DescriptionStandard

        ELQREESPTGPPGSIRTWFQRIPLGWFHCTYQKGKQHCRLRIRQKVEE
    

Molecular Weight5808.58 Da

Isoelectric Point (pI)9.69

Net Charge (pH 7.0)4.00

Net Charge (pH 7.4) 3.69

Charge Density (pH 7.0) 0.0834

GRAVY Index-1.15

Hydrophobic Moment 0.55

Boman Index-0.28

Instability Index58.85

Aliphatic Index 54.79

Aromaticity 0.1042

Extinction Coeff. Reduced 12490.00

Extinction Coeff. Oxidized 12615.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 2457.59

LogP -22.92

H-bond Donors 88.0

H-bond Acceptors 78.0

Rotatable Bonds 191.0

Heavy Atoms 410.0

Ring Count 13.0

Amide Bonds 52.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0286712 VERIFIED: YES

Provenance & Taxonomy

Organismnot reported [other]

Structure & Mods

Configlinear peptide; DSSP H 37.5%, E 20.8%, T 22.9%, C 18.8% [Linear]

Chiralitycanonical L-amino-acid peptide [L]

N-TermNone

C-TermNone

Bio-Activity Profile

Function

Antiviral Antimicrobial

RECORD: Rec_0383738 VERIFIED: YES

Provenance & Taxonomy

OrganismZaire ebolavirus [Virus]

FamilyVirus-derived peptide

Tax ID186538;0

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antiviral Entry inhibitor

TargetEbola virus (Virus entry); Vero E6

Activity0.025 μM

MethodFlow cytometry

PaperEbolavirus delta-peptide immunoadhesins inhibit marburgvirus and ebolavirus cell entry. | Radoshitzky SR, Warfield KL, Chi X, Dong L, Kota K, Bradfute SB, Gearhart JD, Retterer C, Kranzusch PJ, Misasi JN, Hogenbirk MA, Wahl-Jensen V, Volchkov VE, Cunningham JM, Jahrling PB, Aman MJ, Bavari S, Farzan M, Kuhn JH. | J Virol. 2011 | PMID:21697477 PMID21697477 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/21697477/