Peptide Database

Peptide Nameantimicrobial peptides (AMP)

Function Ontology

Antimicrobial

Standard StatusStandard

Sequence Length12 amino acids

Chemical FormulaC70H109N27O16

DescriptionStandard

        GWRNQIRKGWQR
    

Molecular Weight1584.79 Da

Isoelectric Point (pI)12.00

Net Charge (pH 7.0)3.76

Net Charge (pH 7.4) 3.55

Charge Density (pH 7.0) 0.3133

GRAVY Index-2.17

Hydrophobic Moment 0.61

Boman Index-0.63

Instability Index26.66

Aliphatic Index 32.50

Aromaticity 0.1667

Extinction Coeff. Reduced 11000.00

Extinction Coeff. Oxidized 11000.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 755.99

LogP -7.19

H-bond Donors 28.0

H-bond Acceptors 20.0

Rotatable Bonds 53.0

Heavy Atoms 113.0

Ring Count 4.0

Amide Bonds 14.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0107620 VERIFIED: YES

Provenance & Taxonomy

Organismsynthetic construct [Synthetic]

Tax ID32630

Structure & Mods

Configsynthetic linear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

N-TermN-terminal tobramycin conjugation

Other ModsConjugate type: amide; Conjugated small molecule: Tobramycin

Bio-Activity Profile

Function

Antibacterial Antimicrobial

TargetPseudomonas aeruginosa (mid-log phase)

Activity6.25 μM

MethodMIC

RECORD: Rec_0432127 VERIFIED: YES