‹ ›
MYP_015660
← PREVIOUS NEXT → BACK
Basic Information
Buforin-1
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive
Antimicrobial ▸ Antibiotic activity
Antimicrobial ▸ Antifungal
Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic
Standard
39 amino acids
C184H318N70O47
Standard
Sequence
AGRGKQGGKVRAKAKTRSSRAGLQFPVGRVHRLLRKGNY
Physicochemical Analysis
4262.93 Da
12.00
11.88
11.63
0.3045
-0.99
0.83
-0.38
46.12
62.56
0.0513
1490.00
1490.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
1962.60
-24.65
73.0
60.0
150.0
301.0
4.0
41.0
Structural Visualization
3D PDB MODEL
Drag to rotate. Click a residue or atom to inspect it; the selected residue is highlighted in amber in the current view mode. Use the buttons to zoom.
2D CHEMICAL STRUCTURE
Drag to move
Drag to move. Use the buttons to zoom.
Experimental Records
RECORD: Rec_0051880 VERIFIED: YES
Provenance & Taxonomy
Bufo gargarizans [Animal]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
None
①The residue at position 5 is N6-(2-hydroxyisobutyryl)lysine or N6-acetyllysine. ②The residue at position 9 is N6-(2-hydroxyisobutyryl)lysine or N6-lactoyllysine or N6-succinyllysine. ③The Lys13 has a interchain with G-Cter in ubiquitin. ④The Lys15 has a interchain with G-Cter in ubiquitin. ⑤The residue at position 36 is N6-(2-hydroxyisobutyryl)lysine
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative Antifungal
Salmonella typhimurium
4 μg/mL
MIC
PMID8573171;8946958 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/8573171/
RECORD: Rec_0055146 VERIFIED: YES
Provenance & Taxonomy
Bufo gargarizans [Animal]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
None
①The residue at position 5 is N6-(2-hydroxyisobutyryl)lysine or N6-acetyllysine. ②The residue at position 9 is N6-(2-hydroxyisobutyryl)lysine or N6-lactoyllysine or N6-succinyllysine. ③The Lys13 has a interchain with G-Cter in ubiquitin. ④The Lys15 has a interchain with G-Cter in ubiquitin. ⑤The residue at position 36 is N6-(2-hydroxyisobutyryl)lysine
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative Antifungal
Saccharomyces cerevisiae
4 μg/mL
MIC
PMID8573171;8946958 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/8573171/
RECORD: Rec_0080403 VERIFIED: YES
Provenance & Taxonomy
Homo sapiens [Animal]
Buforin
9606
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antifungal
S. pneumoniae, P. putida
4 μg/mL
MIC
PaperA novel antimicrobial peptide from Bufo bufo gargarizans.
RECORD: Rec_0085021 VERIFIED: YES
Provenance & Taxonomy
Bufo gargarizans [Animal]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
None
①The residue at position 5 is N6-(2-hydroxyisobutyryl)lysine or N6-acetyllysine. ②The residue at position 9 is N6-(2-hydroxyisobutyryl)lysine or N6-lactoyllysine or N6-succinyllysine. ③The Lys13 has a interchain with G-Cter in ubiquitin. ④The Lys15 has a interchain with G-Cter in ubiquitin. ⑤The residue at position 36 is N6-(2-hydroxyisobutyryl)lysine
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative Antifungal
Escherichia coli
8 μg/mL
MIC
PMID8573171;8946958 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/8573171/
RECORD: Rec_0087585 VERIFIED: YES
Provenance & Taxonomy
Homo sapiens [Animal]
Buforin
9606
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antifungal
S. mutans
8
MIC
PaperA novel antimicrobial peptide from Bufo bufo gargarizans.
FIRST PREV 1 2 3 4 ... 7 NEXT LAST
Showing 5 records on this page · Page 2 of 7