‹ ›
MYP_015549
← PREVIOUS NEXT → BACK
Basic Information
CMGA 377-391
Antimicrobial
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative
Cardiovascular ▸ Vascular tone modulation ▸ Vasoactive peptide
Cardiovascular ▸ Vascular tone modulation ▸ Vasoconstrictor activity
Hormonal / Endocrine ▸ Hormone peptide
Hormonal / Endocrine ▸ Secretory pathway peptide ▸ Secretory granule peptide
Immunology ▸ Immune modulation ▸ Immunomodulatory activity
Neurological / Signaling ▸ Neuromodulation
Neurological / Signaling ▸ Neuromuscular and muscle activity ▸ Myotropic activity
Neurological / Signaling ▸ Neuropeptide activity ▸ Neuropeptide
Neurological / Signaling ▸ Neuropeptide activity ▸ Neuropeptide precursor
Regulatory peptide ▸ Biological modulation
Regulatory peptide ▸ Biological regulation
Standard
15 amino acids
C73H115N19O28S
Standard
Sequence
LEGEDDPDRSMKLSF
Physicochemical Analysis
1738.87 Da
4.11
-3.23
-3.44
-0.2155
-1.15
0.53
-0.27
30.73
52.00
0.0667
0.00
0.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
776.81
-8.06
26.0
26.0
59.0
121.0
2.0
14.0
Structural Visualization
3D PDB MODEL
Drag to rotate. Click a residue or atom to inspect it; the selected residue is highlighted in amber in the current view mode. Use the buttons to zoom.
2D CHEMICAL STRUCTURE
Drag to move
Drag to move. Use the buttons to zoom.
Experimental Records
RECORD: Rec_0075770 VERIFIED: YES
Provenance & Taxonomy
Rattus norvegicus [Animal]
CMGA
10116
Structure & Mods
linear peptide [Linear]
noncanonical stereochemical modification [Modified]
10:Phosphoserine; 11:Methionine sulfoxide
Bio-Activity Profile
Antimicrobial Anti-Gram-negative Hormone Endocrine Neuropeptide Neuromodulator Vasoactive Vasoconstrictor Metabolic regulation Physiological regulation Myotropic Receptor modulation Immunomodulatory
Mammalian: 5.5 hour; Yeast: 3 min; E. coli: 2 min
PaperNeurotoxin-induced neuropeptide perturbations in striatum of neonatal rats PMID23410195 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/23410195/
RECORD: Rec_0147690 VERIFIED: YES
Provenance & Taxonomy
Rattus norvegicus [Animal]
Chromogranin/secretogranin
10116
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Secretory granule peptide Neuropeptide precursor
PaperNeurotoxin-induced neuropeptide perturbations in striatum of neonatal rats PMID23410195 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/23410195/
RECORD: Rec_0329642 VERIFIED: YES
Provenance & Taxonomy
Rattus norvegicus [Animal]
CMGA
10116
Structure & Mods
linear peptide [Linear]
noncanonical stereochemical modification [Modified]
10:Phosphoserine; 11:Methionine sulfoxide
Bio-Activity Profile
Antimicrobial Anti-Gram-negative Hormone Endocrine Neuropeptide Neuromodulator Vasoactive Vasoconstrictor Metabolic regulation Physiological regulation Myotropic Receptor modulation Immunomodulatory
inhibits catecholamine release from chromaffin cells
Mammalian: 5.5 hour; Yeast: 3 min; E. coli: 2 min
PaperNeurotoxin-induced neuropeptide perturbations in striatum of neonatal rats PMID23410195 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/23410195/
RECORD: Rec_0423884 VERIFIED: NO
Provenance & Taxonomy
Rattus norvegicus [Animal]
10116
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Neuropeptide