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MYP_015530
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Basic Information
RN7-IN6
Anticancer ▸ Cytotoxic anticancer activity ▸ Cytotoxic
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive
Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic
Toxicity / Safety ▸ Cytotoxicity ▸ Cytotoxic
Venom / Toxin ▸ General toxin ▸ Cytotoxic
Standard
13 amino acids
C87H123N23O14
Standard
Sequence
FLGGLIKWWPWRR
Physicochemical Analysis
1715.05 Da
12.00
2.76
2.55
0.2122
-0.24
0.34
0.13
54.04
90.00
0.3077
16500.00
16500.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
600.92
1.19
23.0
17.0
50.0
124.0
8.0
12.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0205839 VERIFIED: YES
Provenance & Taxonomy
Synthetic construct [Synthetic]
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
Amidation
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative
PaperAntimicrobial Activity of Novel Synthetic Peptides Derived from Indolicidin and Ranalexin against Streptococcus pneumoniae. PLoS One. 2015 Jun 5;10(6):e0128532. doi: 10.1371/journal.pone.0128532. PMID: 26046345. PMID26046345 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/26046345/
RECORD: Rec_0206894 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Brevinin
32630
Structure & Mods
Single-chain peptide backbone represented as a linear sequence entry [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative
Pseudomonas aeruginosa ATCC 15442
31.25 μg/mL
MIC
PMID26046345 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/26046345/
RECORD: Rec_0226844 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Brevinin
32630
Structure & Mods
Single-chain peptide backbone represented as a linear sequence entry [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative
S. pneumoniae
7.81-15.62 μg/mL
MIC
PMID26046345 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/26046345/
RECORD: Rec_0276738 VERIFIED: YES
Provenance & Taxonomy
Synthetic construct [Synthetic]
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
Amidation
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative
Streptococcus pneumoniae(30 clinical isolates)
7.81-15.62 μg/mL
MIC
PaperAntimicrobial Activity of Novel Synthetic Peptides Derived from Indolicidin and Ranalexin against Streptococcus pneumoniae. PLoS One. 2015 Jun 5;10(6):e0128532. doi: 10.1371/journal.pone.0128532. PMID: 26046345. PMID26046345 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/26046345/
RECORD: Rec_0288610 VERIFIED: YES
Provenance & Taxonomy
Synthetic construct [Synthetic]
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
Amidation
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative
Klebsiella pneumoniae
250 μg/mL
MIC
PaperAntimicrobial Activity of Novel Synthetic Peptides Derived from Indolicidin and Ranalexin against Streptococcus pneumoniae. PLoS One. 2015 Jun 5;10(6):e0128532. doi: 10.1371/journal.pone.0128532. PMID: 26046345. PMID26046345 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/26046345/
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